Scientist - Bispecifics and Antibody Engineering

About the Role

Join our Bispecifics and Antibody Engineering Department to support the production, purification, and functional characterization of next-generation antibodies across multiple programs. Your work will directly impact the therapeutic pipeline and contribute to the development of new platform capabilities in a fast-paced, collaborative environment.

Responsibilities

• Perform molecular biology techniques to generate expression constructs, including DNA isolation and sequence confirmation
• Conduct transfections for protein production at multiple scales
• Purify biologics using chromatography platforms, including affinity, ion exchange (IEX), and size-exclusion chromatography on ÄKTA systems
• Characterize proteins via immunoblotting, SDS-PAGE, thermal stability, and UV/Vis spectrophotometry
• Perform properly controlled biochemical and cell-based assays (e.g., ELISA, AlphaLISA, flow cytometry, phagocytosis, cell activation, and cytolytic assays)
• Troubleshoot bioanalytical and cell-based assay data to inform iterative optimization
• Collaborate with colleagues to evaluate biological function in vivo
• Maintain accurate records in Benchling and electronic lab notebooks (ELN)

Requirements

• B.Sc., M.Sc., or related degree in molecular biology, cell biology, biochemistry, immunology, or a related field
• 5+ years of relevant academic or industry experience
• Strong attention to detail and a rigorous approach to experimentation
• Excellent organizational, communication, and presentation skills
• Ability to prioritize and adapt quickly to evolving program directions and timelines

Preferred Qualifications

• Hands-on experience with cloning, antibody expression, antibody purification and characterization, and cell-based bioassays
• Experience with in vivo disease modeling

Benefits

Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role:

• Annual bonuses or other incentive plans
• Equity awards
• Pension or retirement benefits, 401(k) company match
• Health and wellness programs, fitness centers
• Insurance benefits (e.g., medical, dental, vision, life, and disability)
• Paid time off and family support benefits

Pay

Salary Range (annually): $93,900.00 - $153,300.00

Schedule

This is an onsite position located in Tarrytown, NY.