Jobs · Analyst · Maryland

Scientist Bioscience

Zenith LifeScience · Gaithersburg, MD · 1 mo ago
On-siteAnalystFull-time
We need to output HTML fragment with sections: h3 headings for sections present. No job title heading. No Job ID. No boilerplate. We need to preserve all substantive info. We have location, duration, description, responsibilities, day-to-day responsibilities, required education & skills, desirable experience, key behaviours and competencies. We need to decide sections: About the role (maybe from description), Responsibilities (key responsibilities), Day-to-day Responsibilities (could be part of responsibilities but we can combine? The instruction: prefer few substantive sections over many thin ones. Could combine responsibilities and day-to-day into one Responsibilities section. But we have separate headings: "Key Responsibilities" and "Day-to-day Responsibilities". Might be okay to have one Responsibilities section covering both. However we need to include sections only when posting has real specific content. It does. We could have sections: About the role, Responsibilities, Required Education & Skills, Desirable Experience, Key Behaviours and Competencies. Possibly also Duration? Not a section heading; could be in a paragraph. We must not create Pay/Schedule/Benefits sections because not present. We need to use

for section headings. Use
  • for any list of duties/requirements/benefits, and

    for prose. We need to preserve all substantive info; not invent or summarize away detail. So we need to include all bullet points as list items. We need to remove boilerplate: cookie/navigation/legal/EEO etc. Not present. We need to not repeat job title as heading. We need to not put Job ID/requisition numbers as headings. We need to output only HTML fragment. Let's craft:

    Location: Gaithersburg, MD (100% onsite)

    Duration: until the end of the year (four-month opportunity)

    Then

    About the role

    with paragraph summarizing description. Then

    Responsibilities

    with
    • ... combine key responsibilities and day-to-day responsibilities. Then

      Required Education & Skills

      with
      • ... Then

        Desirable Experience

        with
        • ... Then

          Key Behaviours and Competencies

          with
          • ... Make sure to preserve details exactly as in text, but we can paraphrase? The instruction: preserve ALL substantive information; do NOT invent or summarize away detail. So we should not lose details; we can keep them as list items but we can keep the phrasing similar. It's okay to slightly rephrase but must keep meaning. Safer to copy the sentences. Let's extract bullet points. Key Responsibilities list: - Supporting the development and execution of high-throughput microbial colony screening workflows using automated liquid-handling systems. - Preparing microbial cultures, samples, reagents, and assay plates in accordance with approved experimental protocols. - Operating and learning to program automated laboratory equipment for liquid transfer, dilution, plate preparation, and sample processing. - Screening mutant libraries and assessing glycoprotein production using appropriate analytical methods, including immunoassays such as ELISA. - Performing routine molecular biology techniques, which may include DNA extraction, PCR, plasmid preparation, transformation, and agarose gel electrophoresis. - Supporting the evaluation and optimization of microbial libraries to identify improved glycoprotein-producing candidates. - Contributing to sample preparation and data generation for whole-genome sequencing and related genomic analysis activities. - Supporting experiments involving enzymatic glycosylation and the characterization of glycoprotein production. - Recording experimental procedures, observations, and results accurately in electronic laboratory systems and approved documentation. - Analysing experimental data, identifying trends, and communicating findings to project team members. - Following all relevant laboratory, biosafety, quality, data integrity, and company procedures. Day-to-day Responsibilities list (paragraph style but we can convert to list): - Spend most of the day supporting experiments in the lab. - Set up and operate automated workflows and laboratory equipment. - Plan experiments and determine the required reagents and materials. - Prepare plates and other materials for robotic processing. - Support high-throughput culture workflows. - Manage or monitor automated colony-picking and sample-processing steps. - Allow the automated system to grow samples, collect aliquots, and transfer them into assays. - Run high-throughput assays, including ELISA/immunoassays. - Monitor individual workflow steps and understand the importance and criticality of each operation. - Analyze and evaluate the data generated by the automated assays. - Follow established methods and protocols accurately. - Work closely with the manager and project team to understand both the biology and chemistry behind the workflow. - Maintain a strong sense of responsibility, organization, and ownership over the experiments. - Work primarily onsite in the lab, while spending time at a desk for data analysis and experiment planning. We can combine both lists into one Responsibilities section. Required Education & Skills bullet points: - The ideal candidate will have a Masters degree or PhD in molecular biology, biochemistry, microbiology, biotechnology, bioengineering, or a related scientific discipline. - Candidates with a Bachelors degree and relevant laboratory experience may also be considered, depending on their practical expertise. - The candidate should have hands-on knowledge of molecular biology techniques, microbial culture, and immunoassay methods, preferably including ELISA. - Experience with bacterial expression systems, protein or glycoprotein production, colony screening, library screening, or assay development would be advantageous. - The role requires a careful and methodical approach to laboratory work, with the ability to follow protocols consistently while also contributing ideas to improve experimental workflows. - The successful candidate should be comfortable working with repetitive, high-throughput experiments, analysing quantitative data, and maintaining accurate records. Desirable Experience bullet points: - Experience in one or more of the following areas would be beneficial: - High-throughput screening or automated liquid-handling platforms. - Bacterial strain engineering, transformation, or mutant library generation. - Recombinant protein or glycoprotein expression and characterization. - ELISA development, optimization, or other plate-based immunoassays. - Whole-genome sequencing sample preparation or interpretation of sequencing results. - Enzymatic glycosylation or glycoengineering. - Laboratory automation, liquid-handler programming, or integration of automated workflows. - Data analysis using tools such as Excel, GraphPad Prism, or equivalent software. - Work in an industrial, regulated, biotechnology, pharmaceutical, or vaccine-development environment. Key Behaviours and Competencies bullet points: - The successful candidate will demonstrate strong attention to detail, effective organisation, and the ability to manage multiple experiments within agreed timelines. - They should be able to work independently on defined tasks while collaborating effectively with scientists and technical colleagues. - Clear communication, reliable documentation, sound experimental judgement, and a commitment to laboratory safety and data integrity are essential. - The candidate should also show enthusiasm for learning new technologies, particularly laboratory automation, genomics, glycoprotein production, and high-throughput process development. Now About the role paragraph: from description: "The Bacterial Vaccines Biochemistry Team is seeking a motivated Upstream Process Development Contractor to support the optimization of microbial glycoprotein production. The successful candidate will contribute to a high-throughput screening programmed designed to identify microbial colonies with enhanced glycoprotein expression from a library of mutants. The role will involve the use of automated liquid-handling platforms to support experimental workflows, including colony screening, sample preparation, assay set-up, and data generation. The contractor will work closely with scientists across upstream process development, molecular biology, analytical biochemistry, and automation. This is a four-month opportunity suited to a candidate with practical experience in molecular biology techniques and immunoassays, together with an interest in developing expertise in laboratory automation, whole-genome sequencing, enzymatic glycosylation, library optimization, and high-throughput bioprocessing." We need to preserve that. Now location and duration: we can put in a

            maybe with strong tags. We must not create Pay/Schedule/Benefits sections. Now output HTML fragment. Let's craft:

            Location: Gaithersburg, MD (100% onsite)

            Duration: until the end of the year (four‑month opportunity)

            About the role

            The Bacterial Vaccines Biochemistry Team is seeking a motivated Upstream Process Development Contractor to support the optimization of microbial glycoprotein production. The successful candidate will contribute to a high-throughput screening programmed designed to identify microbial colonies with enhanced glycoprotein expression from a library of mutants. The role will involve the use of automated liquid-handling platforms to support experimental workflows, including colony screening, sample preparation, assay set-up, and data generation. The contractor will work closely with scientists across upstream process development, molecular biology, analytical biochemistry, and automation. This is a four-month opportunity suited to a candidate with practical experience in molecular biology techniques and immunoassays, together with an interest in developing expertise in laboratory automation, whole-genome sequencing, enzymatic glycosylation, library optimization, and high-throughput bioprocessing.

            Responsibilities

            • Supporting the development and execution of high-throughput microbial colony screening workflows using automated liquid-handling systems.
            • Preparing microbial cultures, samples, reagents, and assay plates in accordance with approved experimental protocols.
            • Operating and learning to program automated laboratory equipment for liquid transfer, dilution, plate preparation, and sample processing.
            • Screening mutant libraries and assessing glycoprotein production using appropriate analytical methods, including immunoassays such as ELISA.
            • Performing routine molecular biology techniques, which may include DNA extraction, PCR, plasmid preparation, transformation, and agarose gel electrophoresis.
            • Supporting the evaluation and optimization of microbial libraries to identify improved glycoprotein-producing candidates.
            • Contributing to sample preparation and data generation for whole-genome sequencing and related genomic analysis activities.
            • Supporting experiments involving enzymatic glycosylation and the characterization of glycoprotein production.
            • Recording experimental procedures, observations, and results accurately in electronic laboratory systems and approved documentation.
            • Analysing experimental data, identifying trends, and communicating findings to project team members.
            • Following all relevant laboratory, biosafety, quality, data integrity, and company procedures.
            • Spend most of the day supporting experiments in the lab.
            • Set up and operate automated workflows and laboratory equipment.
            • Plan experiments and determine the required reagents and materials.
            • Prepare plates and other materials for robotic processing.
            • Support high-throughput culture workflows.
            • Manage or monitor automated colony-picking and sample-processing steps.
            • Allow the automated system to grow samples, collect aliquots, and transfer them into assays.
            • Run high-throughput assays, including ELISA/immunoassays.
            • Monitor individual workflow steps and understand the importance and criticality of each operation.
            • Analyze and evaluate the data generated by the automated assays.
            • Follow established methods and protocols accurately.
            • Work closely with the manager and project team to understand both the biology and chemistry behind the workflow.
            • Maintain a strong sense of responsibility, organization, and ownership over the experiments.
            • Work primarily onsite in the lab, while spending time at a desk for data analysis and experiment planning.

            Required Education & Skills

            • The ideal candidate will have a Masters degree or PhD in molecular biology, biochemistry, microbiology, biotechnology, bioengineering, or a related scientific discipline.
            • Candidates with a Bachelors degree and relevant laboratory experience may also be considered, depending on their practical expertise.
            • The candidate should have hands-on knowledge of molecular biology techniques, microbial culture, and immunoassay methods, preferably including ELISA.
            • Experience with bacterial expression systems, protein or glycoprotein production, colony screening, library screening, or assay development would be advantageous.
            • The role requires a careful and methodical approach to laboratory work, with the ability to follow protocols consistently while also contributing ideas to improve experimental workflows.
            • The successful candidate should be comfortable working with repetitive, high-throughput experiments, analysing quantitative data, and maintaining accurate records.

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