Jobs · Research · Massachusetts

Research Scientist I - Viral Genomics Group - Sabeti Lab

Broad Institute of MIT and Harvard · Cambridge, MA · 1 mo ago
Research$88k–$124k/yrFull-time

About the role

The role is part of the Sabeti Lab's work as a CDC’s Pathogen Genomics Center of Excellence (PGCoE) and within NIH’s Human Virome Program (HVP), developing and scaling novel genomic methods to track the spread and evolution of viruses and other pathogens and characterize the largely unexplored collection of viruses and bacteriophages present in healthy humans.

This position offers an excellent opportunity to participate in a dynamic research environment where teaching and mentorship are a priority. Your work will be central to several major research projects and efforts to advance genomic surveillance of pathogens and cataloging of commensal viruses, including collaborations with other groups at the Broad Institute, across the United States, and internationally.

Key Responsibilities

  • Drive the innovation of agnostic metagenomic sequencing and other NGS technologies, including enrichment and depletion strategies to maximize viral signal detection in complex metagenomic samples.
  • Design and implement automated laboratory workflows; work closely with automation engineers to scale tech dev protocols for high-throughput production environments.
  • Lead cross-functional teams and collaborate with internal and external partners to achieve project objectives. Navigate complex organizational structures to ensure alignment between laboratory results and computational requirements.
  • Support the strategic aims of both HVP (discovery of novel viral dark matter) and PGCoE (public health outbreak response) through the implementation of robust genomic tools.
  • Contribute to high-impact publications and contribute to grant strategy for expanding virome and pathogen genomics research.
  • Mentor and supervise Research Associates; provide career development guidance and manage performance within the matrixed framework.

Requirements

  • Education: PhD in Genetics, Genomics, Molecular Biology, or a related field.
  • Experience: 0-2 + years of postdoctoral or relevant professional experience.
  • Demonstrated experience working and leading within a matrixed team environment is a plus.
  • Technical Skills: Advanced expertise in sample preparation and Illumina NGS technologies, including a deep understanding of kit chemistries and reagents; proven track record in developing and optimizing molecular biology protocols; experience with laboratory automation and scaling genomic assays; proficiency in cloud-based genomic analysis is highly desirable.

Competencies

  • Elevated scientific creativity and complex problem-solving skills.
  • Excellent communication and negotiation skills for representing the Broad at HVP and PGCoE consortium meetings.
  • Resilience and the ability to drive progress in a fast-paced, collaborative environment.

Pay

Pay Range: $88,000.00/yr - $124,000.00/yr

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