Research Lab Technician II - OHNS Cancer Research

Job Summary

Carries out a broad range of technically advanced research activities and procedures; evaluates conclusions and has considerable latitude to modify or devise methods and techniques as necessary to achieve desired results; typically supervises technical and sometimes administrative elements of the research unit.

Essential Functions

• Executes protocols of non-routine experiments.
• Aids Principal Investigator in determining the most suitable methodology.
• Performs basic design and modification of protocols.
• Calculates, transcribes, and analyzes data.
• Presents reports.
• Organizes and summarizes acquired data using scientific and statistical techniques.
• Participates in the design of experiments or field work.

Qualifications

• Education: Bachelor's Degree in Biology, Biochemistry, Biomedical Engineering, or a related field is required.
• Licenses and Credentials: Experience: Previous Research Lab Experience 1-2 years required.

Knowledge, Skills And Abilities

• Analytical skills and ability to resolve technical problems.
• Ability to interpret acceptability of data results.
• Strong Computer skills.
• Demonstrated competence in research techniques and methodologies.

Additional Job Details

Job Description: Research Lab Technician II (RLT II)

Responsibilities

• Carries out a broad range of experimental and analytical activities, including:
  • In vivo mouse tumor models: Establishing, maintaining, and monitoring murine tumor models; performing tumor implantation, measurements, and longitudinal study support; handling and processing of mouse tissues following in vivo experiments; supporting ex vivo tissue preparation and analysis, including sample preservation for downstream assays.
  • Cell biology and in vitro systems: Maintaining routine mammalian cell culture; establishing and expanding primary cell lines from tumor or tissue specimens; performing cell-based assays to evaluate biological responses to therapeutic or imaging agents; supporting experimental design and execution of mechanistic studies in vitro.
  • Molecular and biochemical techniques: Tissue processing for downstream molecular analyses; extraction of DNA, RNA, and proteins from tissue and cell samples; western blotting, immunodetection, and related protein analysis techniques; flow cytometry and sample preparation for immune and tumor cell profiling; supporting downstream data interpretation in collaboration with investigators.
  • Imaging and technology development: Participation in ex vivo tissue imaging and fluorescence-based assays; exposure to advanced fluorescence lifetime imaging and other optical imaging modalities developed in the laboratory; assisting with instrument testing, validation, and experimental imaging workflows; imaging expertise is not required at entry level and will be developed through on-the-job training.
  • Data analysis and computational support: Performing data analysis using commercial and laboratory-developed software tools; exposure to image processing and quantitative analysis pipelines; experience with programming languages such as Python or MATLAB is highly desirable but not required.
  • General laboratory and research support: Maintaining accurate experimental records, databases, and sample inventories; assisting with preparation of reports, figures, manuscripts, and presentations; supporting regulatory documentation and compliance requirements as needed; working collaboratively with multidisciplinary team members across basic and clinical research environments.

Qualifications

• A Bachelor of Science degree in Biology, Biochemistry, Biomedical Engineering, or a related field is required, along with 1-2 years of relevant post-baccalaureate laboratory experience.
• Strongly Preferred: The ideal candidate will have demonstrated hands-on experience with animal models and/or a strong background in cell culture and molecular biology techniques, including tissue handling, mammalian cell culture, and standard biochemical assays.
• Strong proficiency in following experimental protocols with precision, maintaining accurate records, and working with biological samples is essential.
• Excellent organizational skills, attention to detail, communication skills, and the ability to work effectively as part of a collaborative research team are required, along with the ability to manage multiple tasks and adapt to shifting experimental priorities in a fast-paced research environment.
• Preferred qualifications include prior experience with mouse tumor models or cancer biology research, as well as familiarity with molecular biology techniques such as Western blotting, nucleic acid extraction, flow cytometry, immunofluorescence, and immunohistochemistry.
• Exposure to biomedical imaging, quantitative assays, or interdisciplinary research environments integrating biology and technology is highly desirable.
• Experience with programming languages such as Python or MATLAB is a strong plus but not required.
• Candidates with a strong interest in transitioning into a highly interdisciplinary program that integrates cancer biology, molecular imaging, and computational analysis are especially encouraged to apply.

Remote Type

Onsite Work Location: 20 Staniford Street Scheduled Weekly Hours: 40 Employee Type: Regular Work Shift: Day (United States of America)

Pay Range

$24.28 - $39.43/Hourly Grade 6

EEO Statement

Massachusetts Eye and Ear Infirmary is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

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At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.