Research Associate Scientist- Spatial Biology (Onsite- Cambridge Crossing, MA)
About the role
We are seeking a Research Associate Spatial Biology for our global pharmaceutical client. You will be a key member of the Translational Development Team, utilizing high-dimensional spatial and genomic profiling tools to address translational knowledge gaps across our development pipelines. The ideal candidate brings hands-on experience in one or more of these areas, strong foundational lab skills, and the ability to work independently and collaboratively to meet project goals.
Responsibilities
- Operate, maintain, and troubleshoot spatial profiling instruments (Phenocycler Fusion, Visium, and related platforms)
- Prepare samples and reagents, including validation and slide preparation
- Support genomic and histological assay workflows
- Maintain accurate records, manage reagent/sample inventory, and perform routine data transfers
- Assist in the development and optimization of new spatial technology reagents and protocols
Requirements
- 3+ years of hands-on laboratory experience
- Prior experience with spatial technologies (e.g., Phenocycler/CODEX, COMET, Visium, CosMx, Xenium, or equivalent platforms), genomics (e.g., scRNA-seq, Illumina Next Generation Sequencing), or histology workflows (e.g., multiplex IF/IHC/ISH on autostainer) — training will be provided for the right candidate
- Familiarity with spatial assay workflows: antibody panel design, staining optimization, and image acquisition/analysis
- Experience with single-cell RNA sequencing (scRNA-seq) or bulk RNA/DNA sequencing using Illumina platforms
- Familiarity with library preparation, sequencing workflows, DV200 test
Preferred
- Histology/Pathology, Cell Culture (Secondary Preference)
- Experience with multiplex immunofluorescence (mIF), IHC, or ISH workflows, particularly on automated autostainer platforms (e.g., Leica Bond, Ventana)
- Basic proficiency in mammalian culture and standard laboratory assays including single cell cloning, CRISPR-Cas9, protein immunoblot and flow cytometry (4+ channels)
Qualifications
- Bachelor's degree in biological sciences, engineering, chemistry, physics, math, computer sciences, or related fields
Pay
$30/hr. - $32.35/hr on W2.
Schedule
This is a 40-hour per-week, 12-month contract (extensions possible), 100% onsite at the client's office in Cambridge Crossing, MA. Candidates must be agreeable with the $20/day parking fee at Cambridge Crossings.
Benefits
This is a W2 role as a Stage 4 Solutions employee. Health benefits and a 401K are offered.