Jobs · Analyst · Massachusetts

Research Associate Scientist- Spatial Biology (Onsite- Cambridge Crossing, MA)

Stage 4 Solutions · Cambridge, MA · 4 wk ago
On-siteAnalyst$20/hrContract

About the role

We are seeking a Research Associate Spatial Biology for our global pharmaceutical client. You will be a key member of the Translational Development Team, utilizing high-dimensional spatial and genomic profiling tools to address translational knowledge gaps across our development pipelines. The ideal candidate brings hands-on experience in one or more of these areas, strong foundational lab skills, and the ability to work independently and collaboratively to meet project goals.

Responsibilities

  • Operate, maintain, and troubleshoot spatial profiling instruments (Phenocycler Fusion, Visium, and related platforms)
  • Prepare samples and reagents, including validation and slide preparation
  • Support genomic and histological assay workflows
  • Maintain accurate records, manage reagent/sample inventory, and perform routine data transfers
  • Assist in the development and optimization of new spatial technology reagents and protocols

Requirements

  • 3+ years of hands-on laboratory experience
  • Prior experience with spatial technologies (e.g., Phenocycler/CODEX, COMET, Visium, CosMx, Xenium, or equivalent platforms), genomics (e.g., scRNA-seq, Illumina Next Generation Sequencing), or histology workflows (e.g., multiplex IF/IHC/ISH on autostainer) — training will be provided for the right candidate
  • Familiarity with spatial assay workflows: antibody panel design, staining optimization, and image acquisition/analysis
  • Experience with single-cell RNA sequencing (scRNA-seq) or bulk RNA/DNA sequencing using Illumina platforms
  • Familiarity with library preparation, sequencing workflows, DV200 test

Preferred

  • Histology/Pathology, Cell Culture (Secondary Preference)
  • Experience with multiplex immunofluorescence (mIF), IHC, or ISH workflows, particularly on automated autostainer platforms (e.g., Leica Bond, Ventana)
  • Basic proficiency in mammalian culture and standard laboratory assays including single cell cloning, CRISPR-Cas9, protein immunoblot and flow cytometry (4+ channels)

Qualifications

  • Bachelor's degree in biological sciences, engineering, chemistry, physics, math, computer sciences, or related fields

Pay

$30/hr. - $32.35/hr on W2.

Schedule

This is a 40-hour per-week, 12-month contract (extensions possible), 100% onsite at the client's office in Cambridge Crossing, MA. Candidates must be agreeable with the $20/day parking fee at Cambridge Crossings.

Benefits

This is a W2 role as a Stage 4 Solutions employee. Health benefits and a 401K are offered.

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