Research Assistant I - Griffin Lab

Classification Minimum Requirements: A bachelor's degree in an appropriate area of specialization and two years of experience or an equivalent combination of education and experience.

About the Role

The Griffin Lab is seeking a motivated research assistant to support studies on nuclear receptor signaling and innate/adaptive immune responses. The successful candidate will perform primary cell culture, characterize immune cell responses, and analyze target gene expression changes using biochemical, molecular, and cellular biology techniques.

Responsibilities

• Isolate, culture, and maintain primary cells.
• Perform immune stimulation assays.
• Quantify target gene expression changes via RT-qPCR and assist with RNA-seq and CUT&RUN sample preparation.
• Maintain cell lines and perform routine molecular biology (RNA/DNA extraction, cloning, western blot).
• Maintain detailed lab notebooks and assist with data analysis/figure preparation.
• Manage lab inventory, reagent ordering, and equipment maintenance.
• Assist with IACUC-related animal procedures (if applicable).

Requirements

• Hands-on experience with primary cell culture and aseptic technique.
• Experience with RT-qPCR and basic molecular biology methods including plasmid transfection.
• Strong organizational skills and attention to detail.

Qualifications

• Preferred MS in immunology, cell biology, molecular biology, or related field.
• Experience with flow cytometry.
• Experience with immune cell isolation and functional assays.
• Familiarity with RNA-seq sample prep or bioinformatics basics.
• Prior experience in an academic research setting.