Research Analyst I - 2nd Shift

About the role

The Immunotoxicology group supports the safety assessment of preclinical treatments and procedures as well as clinical sample analysis using cell based assays including primarily flow cytometry and ELISpot, cell culture and cell isolation, and plate based assays. An array of platforms and instruments are used to support these assays that include BD LSR Fortessa and Cytek Aurora flow cytometers for traditional and spectral cytometry, FCS Express for immunophenotyping analysis, and the ImmunoSpot analyzer for ELISpot. Utilizing these platforms/assays, the teams are responsible for the method development, validation and routine samples analysis in both the regulated and non-regulated space of non-clinical and clinical studies.

Essential Functions

• Efficiently perform and document all procedures, materials and results in compliance with applicable regulatory standards as applicable (protocols, methods, SOPs, etc.)
• Demonstrate effective communication skills through informal discussions with peers, supervisor, and team
• Assist with laboratory maintenance functions
• Independently perform laboratory support functions such as labeling and solution preparations
• Absorb and assist with maintaining study specific inventory of consumables with oversight
• Write both study and non-study deviations with minimal oversight
• Actively participate in process improvement initiatives with oversight
• Develop critical thinking, troubleshooting and time management skills aligned with needs of the operational area
• Absorb and assist in the execution of routine sample analysis studies with oversight
• Absorb and assist in the execution of method validation projects with oversight as needed
• Operate laboratory instruments with complete oversight
• Absorb and assist in the data analysis in appropriate software for at least one analytical platform

Job Requirements

• Minimum of a Bachelor’s degree (BA/BS) in a science related field.
• Ability to communicate verbally and in writing at all levels inside and outside the organization
• Basic familiarity with Microsoft Office Suite
• Computer skills, commensurate with Essential Functions, including the ability to learn validated systems, ability to work extended hours beyond normal work schedule to include, but not limited to evenings, weekends, extended shifts, and/or extra shifts; sometimes on short notice
• Ability to work under specific time constraints
• Ability to work on an ‘on-call’ as needed on a rotational basis
• Must be authorized to work in the United States without a sponsor visa, now or in the future.

About Safety Assessment

Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.

About Charles River

Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

Equal Employment Opportunity

Charles River is an equal opportunity employer and is committed to providing equal employment opportunities for all qualified applicants and employees without regard to race, color, sex, religion, national origin, ancestry, age, mental or physical disability, family status, pregnancy, military or veteran status, or any other characteristic protected by federal, state, or local laws.