R&D Chemist I/II/III

About the role

The R&D Chemist II in the Process Development Group will be responsible for purification, analysis, and isolation of GMP grade peptides under GMP regulations. This work will encompass preparative and analytical chromatography, and lyophilization.

Responsibilities

• Perform preparative and analytical reversed-phase high performance liquid chromatography (HPLC) and isolation operations with direction from supervisor
• Follow written procedures such as Standard Operating Procedures (SOP) and Batch Production Records (BPR)
• Comply with SOP’s in all aspects of the work and follow GMP regulations
• With appropriate training, become well-versed in operation of specific chromatography platforms used in the GMP Manufacturing Group
• Document accurately purification conditions and yields in the Batch Production Records (BPR)
• Work in close cooperation with synthetic chemists to meet project commitments with regard to deliverable timelines, quantity, and quality
• Constantly monitor and improve practices by learning from past projects
• Ensure that all laboratory safety and housekeeping standards are met

Qualifications

• Bachelor's Degree in Chemistry, Biochemistry, or Bioengineering with 3-5 years’ experience
• Master's Degree in Chemistry, Biochemistry, or Bioengineering with 1-3 years’ experience
• Hands-on experience in preparative and analytical reversed-phase high performance liquid chromatography (HPLC) and isolation operations in a GMP environment.
• Hands-on laboratory experience (academic acceptable, industry preferred) in protein or peptide chemistry
• Experience in RP-HPLC and ion exchange chromatography
• Experience with synthesis and/or purification
• Strong knowledge of GMP regulations and ICH guidelines