Program Manager II (Human Research Operations)

About the role

The Division of Neuropsychiatry and Interventional Psychiatry at Mass General Brigham and Harvard Medical School seeks a Program Manager for Research Operations to oversee the execution and operational infrastructure of the Division's research portfolio.

Responsibilities

• Oversee study execution across the full research lifecycle, including protocol development and study start-up, active study operations, participant enrollment and study visits, study closeout and reporting.

• Directly supervise a team of research assistants and junior staff, including hiring, onboarding, supervision, task allocation, performance management, and professional development.

• Ensure appropriate staffing, coverage, and workload allocation across studies.

• Provide ongoing coaching and guidance to research staff to support high-quality study execution and day-to-day operational reliability across studies.

• Serve as the primary operational point of contact for study teams, resolving day-to-day issues and ensuring smooth coordination across projects.

• Support preparation and coordination of administrative and regulatory components of grant applications, working with investigators and pre-/post-award teams to ensure completeness, alignment with study operations, and timely submission.

Qualifications

• Human Research Operations & Team Leadership: Oversee study execution across the full research lifecycle, directly supervise a team, ensure appropriate staffing, and provide coaching and guidance.

• Research Execution Systems & Infrastructure: Develop and maintain systems to support research operations, develop metrics, and build scalable infrastructure.

• Regulatory Compliance, Governance, & Quality Oversight: Oversee regulatory and compliance processes, implement and maintain quality and compliance systems, and ensure adherence to Good Clinical Practice (GCP) standards.

• Administrative Systems & Operational Support: Delegate administrative tasks, build and maintain systems for onboarding and training, equipment and inventory tracking, and operational logs and reporting.

• Cross-Functional Coordination (Research Interface): Ensure research operations align with divisional priorities, coordinate dependencies, and facilitate communication across teams.

Qualifications

• Required:

  • Human Research Operations & Team Leadership: 5+ years of experience in human research operations, clinical trials, or research program management.

  • Research Execution Systems & Infrastructure: Experience with study management systems and building operational systems.

  • Regulatory Compliance, Governance, & Quality Oversight: Demonstrated expertise in regulatory compliance and GCP standards, familiarity with NIH funding mechanisms and research administration processes.

  • Administrative Systems & Operational Support: Strong project management, organizational, and leadership skills.

  • Cross-Functional Coordination (Research Interface): Strong project management, organizational, and leadership skills.

• PREFERRED:

  • Project Management Professional (PMP) or equivalent certification.

  • Certified Research Administrator (CRA), or equivalent certification.

  • Familiarity with academic medical centers or large research organizations.