Principal Scientist - In Vitro Pharmacology & Biology

About The Department

The Diabetes in vitro Biology department is part of the Diabetes US Research area, Diabetes & complications therapeutic area, focusing on research in the cardio-metabolic field, particularly diabetes. This department builds a state-of-the-art research platform, targets, validates, and evaluates novel treatment options, collaborating closely with the Danish part of the organization.

Position

Your key responsibilities will significantly impact our diabetes pipeline, including identifying and evaluating novel therapeutic targets, initiating innovative drug discovery projects, and advancing these through the early pipeline to first-in-human trials. You will guide a global, highly collaborative team in discovery efforts and advise management teams. Additionally, you will contribute to expanding our translational in vitro research platforms.

Essential Functions

• Conduct and summarize non-clinical in vitro studies
• Implement strategies and operations for conducting and summarizing in vitro studies
• Support progression of pipeline projects as project manager and biological coordinator
• Ensure adherence to protocols and regulatory requirements in the execution of in vitro studies
• Analyse and interpret data from in vitro studies to provide insights and recommendations for new drug evaluations
• Collaborate with cross-functional teams to ensure the successful implementation of experiments and the generation of high-quality data
• Develop and improve in vitro models supporting non-clinical studies
• Identify and evaluate new therapeutic targets and principles by exploring and improving in vitro models
• Contribute to the design and validation of new in vitro models to support target validation, target maturation, and mode-of-action studies
• Stay updated on the latest scientific advancements and technologies related to in vitro models and propose innovative approaches for their development and utilization
• Communicate data internally, externally, and in regulatory submissions
• Prepare clear and concise reports summarizing in vitro study findings for internal stakeholders, external collaborators, and regulatory submissions
• Present in vitro data and its implications to cross-functional teams, management, and external partners
• Accurately and timely communicate in vitro data to support decision-making processes and regulatory requirements

Qualifications

• Master’s degree with 12+ years of relevant experience, or PhD with 8+ years of relevant experience required
• Proven scientific track-record and thorough understanding of Diabetes pathophysiology and relevant in vitro systems, including experience with target ideation and maturation, preferred
• Experience in small molecule drug development paths, preferred
• Strong knowledge and understanding of the pharmaceutical industry and drug discovery processes
• Demonstrated ability to communicate and present scientific data internally, externally, and in regulatory submissions
• Understanding and experience using systems biology, bioinformatic analysis, scRNAseq/snRNAseq and RNAseq analyses, preferred
• Experience in developing and improving in vitro models supporting non-clinical studies
• Track record of identifying and exploring new therapeutic targets and principles
• Mentorship experience in the field of expertise is preferred

Pay

The base compensation range for this position is $185,000 to $230,000. Base compensation is determined based on a number of factors. This position is also eligible for a company bonus based on individual and company performance.

Benefits

• Novo Nordisk offers long-term incentive compensation and/or company vehicles depending on the position's level or other company factors.
• Employees are eligible to participate in Company employee benefit programs including medical, dental, and vision coverage; life insurance; disability insurance; 401(k) savings plan; flexible spending accounts; employee assistance program; tuition reimbursement program; and voluntary benefits such as group legal, critical illness, identity theft protection, pet insurance, and auto/home insurance.