Jobs · OTHR · Massachusetts

Principal Scientist - Global Drug Discovery

BioSpace · Lexington, MA · 2 wk ago
OTHR$180k–$235k/yrFull-time

About the role

The Principal Scientist will provide scientific leadership in the identification, and validation, and advancement of new drug targets related to CNS-obesity biology and appetite regulation. The role will drive in vivo pharmacology strategies across early and late-stage pipeline programs, enabling translation of novel biology into therapeutic opportunities.

Responsibilities

  • Hands-on for planning and designing in vivo pharmacology studies, working with technical scientists, and advising on the execution, interpretation, as well as communication of results of complex state of the art in vivo experiments.
  • Proven subject matter expertise related to CNS-obesity biology and appetite regulation. Demonstrates a specialized depth and/or breadth of expertise, and engages relationships with other key areas related to drug development in the pharmaceutical industry.
  • Provide expert-level guidance for project teams related to experimental strategies to evaluate emerging targets, biology or technologies.
  • Evaluate emerging targets and technologies and propose and oversee external collaborations.
  • Lead cross-functional project teams (in vitro, omics, translational, clinical teams).
  • Contribute subject matter expertise to develop the research agenda with a clear understanding of the link between scientific project goals and overall long-term business needs.
  • Propose new projects that support the strategic agenda and address gaps in technological capabilities and therapeutic areas, related to obesity and appetite regulation.
  • Represent the organization through external communication of impactful scientific research in the form of presentation at external conferences and publication in scientific journals and patents.
  • Maintain a deep understanding of theoretical knowledge and a connection to the external scientific community through continuous evaluation of relevant literature.
  • Guide and/or lead global, cross-functional experimental teams to achieve project goals.
  • Provide mentorship and training to colleagues within field of expertise.
  • Guide other research teams regarding suitable assays/techniques to interpret and translate in vivo studies to progress the obesity pipeline.

Qualifications

  • Bachelor’s degree with 22+ years’ relevant experience required, or Master's Degree with 16 years relevant industry experience required, or PhD with 10 years’ relevant industry or post-doctorate experience can be considered.
  • Relevant required experience includes:
    • Insert subject matter expertise.
  • Preferred experience includes:
    • Insert subject matter preferred experience.
  • Demonstrates excellent verbal and written communication skills.

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