Principal Scientist, Cancer Early Detection

Job Summary

ICR's Cancer Early Detection program focuses on building early warning systems using arrays of blood- and urine-based biomarkers from cancer patients and healthy controls, primarily at stages zero, one, and two. The Principal Scientist will lead this team in predicting cancer signatures to enable early intervention.

Responsibilities

• Lead a cutting-edge cancer biomarkers group with the goal of detecting cancer at its earliest stages
• Contribute practical and translatable ideas for pan-cancer screening, early detection, diagnostics, prevention, and therapeutics
• Quantify and track cancer biomarkers, including circulating tumor cells (CTCs), circulating tumor DNA (ctDNA), serum, plasma, and urine proteins, RNA, metabolites, driver-gene mutations, epigenetic modifications, etc
• Collaborate with ICR's Biomarkers Team to perform molecular and cellular cancer prevention screening assays, under a personalized medicine paradigm

Requirements

• A PhD, MD, or both
• At least 10 years of cancer research experience, preferably in early detection and biomarkers
• Current and in-depth knowledge of pan-cancer: screening, early detection, biomarkers, diagnostic prediction, genetics, prevention, and chemical and vaccine-therapeutics (practical and experimental)
• Programming experience in R and Python
• Solid grasp of biostatistics, especially probability theory
• Experience with prediction modeling and machine learning, including experience using proper scoring rules

Benefits

• Ideal candidates will have expert knowledge and understanding of worldwide cancer biomarker and detection assay development pipelines
• Experience with cell-based assays, immunofluorescent microscopy, qPCR, flow cytometry, single-cell genomics, RNAseq, cell culture, organoid culture, Illumina NextSeq 550, DNA methylation sequencing, ddPCR, Luminex, clinical chemistry instrumentation, Kryptor, Access 2, robotic liquid handling (e.g. Tecan), Vortex, and DepArray
• Experience with protein, RNA, and small metabolite cancer biomarker analysis

Qualifications

• An easygoing, friendly personality
• The ability to work in the United States without sponsorship

Pay

Starting base pay range: $165,000/yr - $205,000/yr
Starting additional compensation range: $7,500/yr - $20,000/yr

Schedule

Full time

About the Role

Join a small-group, highly collaborative work environment dedicated to advancing personalized medicine and preventing major age-related diseases through regenerative and preventive interventions.

Contact

To apply, please visit our website at www.invitrocellresearch.com.

Company

InVitro Cell Research, LLC (ICR) is a privately funded company focused on regenerative and preventive personalized medicine. We are dedicated to discovering and developing interventions to slow and reverse biological aging and prevent major age-related diseases.

Location

Fort Lee, New Jersey, 07605, United States