Postdoctoral Scientist – Fibrosis, Liver Disease

About the role

The Inflammation Biology group at Gilead is seeking a passionate and driven postdoctoral scientist to pursue innovative research at the forefront of chronic fibrotic liver disease. This role offers a unique opportunity to explore the complex biology of conditions such as metabolic dysfunction-associated steatohepatitis (MASH), primary biliary cholangitis (PBC), and primary sclerosing cholangitis (PSC).

Responsibilities

• Lead independent research projects to investigate pathogenic mechanisms in chronic fibrotic liver disease.
• Utilize Gilead's single cell and spatial transcriptomic datasets as well as clinical datasets to uncover novel mechanisms driving fibrotic niche expansion.
• Use a combination of mouse genetic and pharmacology approaches to investigate key disease drivers and establish novel ex vivo models allowing for target identification and screening.
• Work with a mentor to design, conduct, and analyze in vitro and in vivo experiments to drive research towards publication in a top-tier journal.
• Publish work in top-tier journals and present at scientific conferences.

Requirements

• Ph.D. in biochemistry, molecular biology, immunology or related discipline.
• At least one first author paper published or accepted in a peer-reviewed journal.
• Proficiency in mammalian cell biology and biochemistry techniques.
• Excellent written, verbal, and interpersonal communication skills and strong organizational skills are required.

Preferred Qualifications

• Broad hands-on expertise in cell biology, molecular biology, biochemistry and imaging techniques including in vitro cell-based functional assays, primary cell cultures, transfection/transduction techniques, CRISPR/Cas9, microscopy, flow cytometry, and other immunoassays.
• Hands-on experience with mouse models of disease, mouse handling, in-life procedures and tissue harvesting.
• Familiarity with the analysis of large-scale multiomic datasets, such as single-cell and spatial transcriptomics.
• Experience developing complex primary cell co-culture systems.

Qualifications

• Demonstrated success in leading focused hypothesis-driven biological research, as exemplified by quality publications.
• Experience working in a cross-functional and highly collaborative team environment.
• Strong communication skills, both verbal and in writing, to a variety of audiences.

Benefits

• Salary range: $126,820.00 - $164,120.00.
• Paid time off and a benefits package.
• Company-sponsored medical, dental, vision, and life insurance plans.
• No discretionary annual bonus or discretionary stock-based long-term incentives.

Contact

• For additional benefits information, visit here.