Postdoctoral researcher in neurodegenerative disease and cancer

About the role

The laboratory of Professor Xiaolu Yang at the Perelman School of Medicine, University of Pennsylvania, is seeking a highly motivated postdoctoral researcher to join our dynamic and interdisciplinary team.

Responsibilities

• Investigate the fundamental mechanisms that drive neurodegenerative disease and cancer, with current projects centered around two major research areas: Protein quality control, aging, and neurodegenerative diseases and Tumor suppression, metabolism, and autophagy.
• Contribute to ongoing work defining the molecular mechanisms of two previously unrecognized protein quality control (PQC) systems involving tripartite motif (TRIM) proteins and poly-Asp/Glu (polyD/E) proteins.
• Explore the contributions of these pathways to aging and neurodegenerative diseases (Alzheimer’s, Parkinson’s, ALS).
• Identify metabolic changes that promote tumor initiation and progression.
• Examine the regulatory mechanisms and functional roles of the tumor suppressor p53, including its control of metabolic pathways essential for biosynthesis and redox balance.
• Identify metabolic changes that influence the biology of embryonic and cancer stem cells.

Requirements

• Hold, or be nearing completion of, a PhD or MD degree.
• Demonstrate a strong publication record.
• Show rigorous experimental skills.
• Have relevant experience in areas such as biochemistry, cell biology, molecular biology, metabolism, stem cell biology, neuroscience, cancer research, or animal models.

Qualifications

• Strong publication record.
• Rigorous experimental skills.
• Relevant experience in areas such as biochemistry, cell biology, molecular biology, metabolism, stem cell biology, neuroscience, cancer research, or animal models.

Skills

• Strong background in biochemistry, cell biology, molecular biology, metabolism, stem cell biology, neuroscience, cancer research, or animal models.

Benefits

Not specified.

Pay

Not specified.

Schedule

Not specified.

Contact Information

• Review of applications will begin immediately and will continue until the position is filled.
• Applications should be sent through Interfolio using the link below and include: Cover Letter; Curriculum vitae; Contact intormation tor three references.