POSTDOCTORAL ASSOCIATE - Cell Biology & Chemical Biology - Calibr-Skaggs

Position Summary

The candidate will join an early-stage discovery research group at Calibr-Skaggs. Under guidance and in collaboration with others the candidate will perform research in the areas of biochemistry and protein engineering. Specifically, the candidate will discover, characterize, and optimize toxin-neutralizing antibodies and monobodies for human therapeutic use. The drug discovery pipeline at Calibr-Skaggs spans early discovery to IND, and the candidate will be engaged throughout this process.

A successful candidate will be self-led and able to work both independently and collaboratively to lead research projects, analyze data and interpret results. The right candidate will be adaptable with a willingness to collaborate with others on a wide range of projects, and enthusiastically learn new skills/techniques.

Responsibilities

• Work within discovery project teams and with scientists across different functional areas and be expected to present her or his work at project team meetings and to research leadership
• Work independently to design, execute, analyze, interpret and troubleshoot scientific experiments in molecular biology and biochemistry
• Accurately maintain written reports and present results in an organized and timely manner to research leadership
• Communicate effectively with peers and supervisors, foster teamwork and contribute to collaborative efforts
• Develop and implement robust bacterial protein expression and purification workflows
• Characterize biochemical and biophysical properties of candidate antibody/monobody therapeutics
• Establish biochemical and cell-based enzymatic activity and protein-protein interaction assays

Qualifications

• Candidates should possess strong foundational research skills, along with a solid understanding of molecular biology, biochemistry, and related biological techniques, including assay development.
• Experience with directed evolution techniques is a plus but is not required.
• Successful candidates will have the opportunity to apply their research expertise while developing knowledge and hands-on experience in drug discovery and development within a collaborative research environment.

Requirements

• Requires a PhD in biochemistry, chemical biology, or related area or an equivalent combination of education and training.
• A strong track record of research productivity.
• Highly motivated, creative, and devoted to project goals.
• Able to collaborate proficiently and communicate effectively with colleagues and management teams.
• Able to contribute in a meaningful way to scientific discourse.

Physical Requirements

This position works in a laboratory or vivarium environment.

Compensation

Postdoctoral Associates will be hired following the National Institute of Health and California’s exempt salary guidelines, which provide for a starting range of $70,304- $75,353 per year. Consideration will be given to experience that exceeds the listed requirements.

Benefits

• Comprehensive Benefits Include Eligibility for retirement plans with employer contribution.
• Full suite of Health and Welfare plans including four medical plan options (including an HSA available option), dental, vision, life insurance, disability, EAP and more.
• Paid Time Off - 5 days annually.
• Free, on-site Counseling Center which provides confidential counseling services to benefits-eligible employees.
• Free, on-site parking.
• Pet Insurance.