Postdoc within Screening of De Novo Designed Proteins
We are seeking a postdoctoral researcher to develop screening tools for identification of high-affinity protein binders. The candidate will participate in a larger, cross-disciplinary project aiming to design screening pipelines for identifying binders for proteins involved in cell wall synthesis in gram-positive bacteria, with the goal of combatting antimicrobial resistance.
The position is part of a project group of four postdocs, each working on different aspects of the project. This specific role focuses on establishing an E. coli-based display system optimized to screen AI-designed proteins for interactions with various targets. The candidate will primarily work in the lab, collaborating with a computational postdoc who will provide sets of designed proteins for wet-lab screening.
About the role
The postdoc’s duties will include research within protein chemistry as well as teaching. The position is for 18 months, starting 15 October 2026 or as soon as possible thereafter.
Requirements
- PhD in protein chemistry, biophysics, or a related field
- Experience with one or more of the following:
- Surface display systems, flow cytometry, FACS, or other cell sorting methods
- Molecular cloning, high-throughput work, E. coli transformation
- E. coli and yeast-based protein production and purification
- Protein-protein interactions using BLI, ITC, SPR, or similar techniques
Benefits
- Terms of employment covered by the Memorandum on Job Structure for Academic Staff
- Salary and appointment terms in accordance with the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State
- Negotiation for salary supplement is possible
Further information about the Department can be found at https://plen.ku.dk/english/. Inquiries about the position may be directed to Assistant Professor Frederik Grønbæk Tidemand (ft@plen.ku.dk) or Morten Petersen, Head of Institute (morten.petersen@plen.ku.dk).