Post Doctoral Scholar - Molecular Medicine & Therapeutics
The Ohio State University Wexner Medical Center · Columbus, OH · 7 mo ago
AnalystFull-time
About the role
Pursues specialized research training, education, and experience under the guidance of the Principal Investigator in the Department of Molecular Medicine & Therapeutics (Nishiga Lab).
Responsibilities
- Plans, designs, and executes experiments of considerable scope and complexity focusing on the mechanisms of heart failure and cardiomyopathies.
- Cultivates and maintains human induced pluripotent stem cells (iPSCs) for reprogramming, maintenance, and differentiation into cardiomyocytes and non-myocyte cells.
- Utilizes CRISPR-Cas9 genome editing to model genetic cardiovascular diseases.
- Performs molecular biology techniques such as qPCR, Western blotting, cloning, and library preparation for omics studies.
- Collects and analyzes data from experiments.
- Prepares and submits fellowship grant applications to secure funding for research projects.
- Contributes to manuscript preparation and publication of research findings.
- Mentors junior lab members and collaborates with other researchers.
- Attends research seminars and participates in professional development activities.
- Performs additional duties as assigned by the Principal Investigator.
Requirements
- Doctoral degree in Biological Sciences, Molecular Biology, Medicine, or related field required.
- Extensive experience with mammalian cell culture and molecular biology techniques.
- Demonstrated expertise in human iPSC culture (reprogramming and differentiation) is strongly preferred.
- Experience with CRISPR/Cas9 genome editing.
- Background in cardiovascular physiology or heart failure mechanisms.
- Proven track record of productivity (first-author publications) and strong scientific writing skills to apply for funding/fellowships.
Qualifications
- Frequent sitting at a computer or microscope.
- Frequent standing to perform bench work.
- Occasionally lifting objects up to 20 lbs (e.g., reagent boxes).
- Requires visual acuity to perform microscopy and analyze data.