Post Doctoral Scholar - Anesthesiology

Position Summary

The Department of Anesthesiology at The Ohio State University College of Medicine is seeking a highly motivated Post-Doctoral Scholar to work in Dr. Xiaowen Bai’s laboratory.

Responsibilities

• Conduct independent and collaborative research using human iPSC-derived neural cells, cerebral organoids, and mouse models.
• Perform electrophysiology and molecular biology experiments, analyze mitochondrial function, conduct live-cell and high-content imaging studies, perform mouse behavioral assays, and contribute to bioinformatics/omics analyses such as scRNA-seq, ATAC-seq, and AI-assisted data analysis.
• Assist in mentoring trainees at various levels, including undergraduate and graduate students, as well as other research trainees.

Minimum Qualifications

• A doctoral degree, such as PhD, MD, MD/PhD, or equivalent, in Biomedical Engineering, Neurobiology, Neuroscience, Cell Biology, Molecular Biology, or a related field is required.
• No prior postdoctoral experience is required.

Preferred Qualifications

• Experience with one or more of the following areas: human iPSC culture, directed differentiation, cerebral organoid models, electrophysiology techniques such as patch-clamp recording or multi-electrode array analysis, molecular biology workflows, mitochondrial assays, live-cell imaging, high-content or automated image analysis, mouse behavioral assays, bioinformatics/omics analysis including scRNA-seq or ATAC-seq, and AI-assisted data analysis.
• Experience with mouse behavioral assays, such as Morris water maze, Y-maze, novel object recognition, open field, elevated plus maze, rotarod, fear conditioning, or related neurobehavioral testing, is preferred.

Additional Information

• The successful candidate will join a collaborative and multidisciplinary research environment within the Department of Anesthesiology at The Ohio State University College of Medicine.
• The position provides opportunities for training in advanced human stem cell-derived models, cerebral organoids, mouse models, electrophysiology, mitochondrial biology, multiomics, bioinformatics, and AI-assisted data analysis.
• The Post Doctoral Scholar will be encouraged to develop independent research projects, contribute to grant applications and manuscripts, present findings at national and international conferences, and build a strong foundation for an independent research career.
• The candidate will also have opportunities to collaborate with investigators across neuroscience, stem cell biology, anesthesiology, mitochondrial biology, genomics, and translational medicine.

Research Areas

• Stem cell biology;
• Cerebral organoids;
• Neurodevelopmental injury;
• Neurodegenerative disease;
• Anesthetic-induced brain injury;
• Alcohol-induced neurodegeneration;
• Mitochondrial dysfunction;
• Redox/calcium signaling;
• Non-coding RNAs;
• Electrophysiology;
• Mouse behavioral assays;
• Multi-omics;
• Bioinformatics;
• AI-assisted data analysis;
• Translational neuroscience.