Postdoctoral Research Fellow, Anesthesiology

Responsibilities

• Experimental Design and Execution Lead and coordinate immunocompetent, orthotopic breast cancer resection models combined with adjuvant chemotherapy.
• Execute complex longitudinal CIPN behavioral assays (mechanical allodynia, cold sensitivity).
• Perform immune specific genetic and pharmacologic manipulations targeting the IRE1α XBP1 pathway.
• Conduct advanced flow cytometry, FACS sorting, molecular assays (qPCR, ELISA), histology, and confocal imaging.
• Mechanistic and Translational Integration Integrate tumor progression endpoints (recurrence, lung metastases, IVIS imaging) with neurotoxicity and immune outcomes.
• Perform ex vivo co culture assays linking immune cell activation to neuronal injury and tumor aggressiveness.
• Evaluate translational pharmacologic strategies (MKC 8866 ± paclitaxel) across multiple disease contexts.
• Data Analysis, Interpretation, and Dissemination Analyze high dimensional data across behavioral, molecular, immune, and oncologic endpoints. Prepare manuscripts, conference presentations, and progress reports for funding agencies.
• Contribute to grant development supporting continuation and expansion of the research program.

Qualifications

PhD or equivalent required.

Benefits

Compensation Base compensation listed within the listed pay range based on factors such as qualifications, skills, relevant experience, and/or training
Premium pay such as shift, on call, and more based on a teammate's job
Incentive pay for select positions
Opportunity for annual increases based on performance

About the Role

This Postdoctoral Fellow position is essential for the successful execution of a highly technical, multi aim translational research project focused on uncovering immune mechanisms underlying chemotherapy induced peripheral neuropathy (CIPN) in the context of breast cancer treatment.