Pediatrics Cytogenetic Lab Specialist I

About the role

The Shivanand R Patil Cytogenetics and Molecular lab, within the Stead Family Department of Pediatrics, is seeking a cytogenetic lab specialist I. The lab utilizes molecular and cytogenetic techniques, including chromosome analysis, fluorescence in situ hybridization (FISH) chromosomal microarray (CMA), and genome sequencing for diagnosis or treatment in cancer and constitutional genetic disorders.

Responsibilities

• Performs cell culture on varieties of tissues received for chromosome analysis according to established protocols.
• Processes cultured cells and prepares slides according to laboratory protocol of chromosome spreads.
• Stains slides utilizing a variety of techniques including G-banding and fluorescent in-situ hybridization for chromosome identification.
• Prepares microscope analysis of metaphases and prometaphase chromosomes for diagnostic purposes.
• Prepares digitized karyotypes using correct International System for Human Cytogenetic Nomenclature (ISCN).
• Performs analysis of fluorescence in situ hybridization (FISH) studies for clinical diagnostic and prognostic purposes.
• Performs chromosomal microarray (CMA) or NGS bench work (wet lab) and initial data analysis.
• Maintains accurate and legible records of all lab results and procedures, and accurately interprets and records test results.
• Participates in lab section meetings with others to discuss quality testing, workflow, efficiency strategies, problematic areas, and laboratory improvement.
• Performs additional tasks as may be assigned by section coordinator or laboratory supervisor such as maintaining records of inventory and ensuring timely ordering of reagents.
• Communicates any problems with equipment to the laboratory supervisor.
• Complies with the appropriate health and safety regulations and work rules.
• Attends and participates in laboratory staff meetings and continuing education programs.
• Demonstrates respect for all members of the University community in the course of performing one’s duties and in response to administrators, supervisors, coworkers, and customers.
• Represents the interests of the University and of unit leadership in the use of resources to meet service and productivity demands within unit goals and budgets; strive to promote continual process and quality improvement.
• Sets up and maintains equipment and supplies.
• May perform functional supervision over support staff.

Requirements

• A bachelor’s degree in biological sciences, Medical Technology, Clinical Laboratory Sciences, a related scientific discipline, or an equivalent combination of education and experience.
• ASCP certification in Cytogenetics or Molecular Biology.
• Must have the visual acuity and analytical skills to distinguish fine detail.
• Ability to work in a fast-paced environment.
• Demonstrated excellent written and verbal communication skills.
• Highly Desired Qualifications:
  • Demonstrated experience in tissue culture techniques for human and other mammalian cells.
  • Demonstrated technical skills in cytogenetic molecular biology as well as preparing slides from tissue for examination.
  • Familiarity with handling and operating digital imaging systems with various software and programs.
  • Familiarity with techniques in FISH and CMA.
  • Familiarity with high throughput DNA sequencing (also called next generation sequencing).

Qualifications

• Demonstrated experience in tissue culture techniques for human and other mammalian cells.
• Demonstrated technical skills in cytogenetic molecular biology as well as preparing slides from tissue for examination.
• Familiarity with handling and operating digital imaging systems with various software and programs.
• Familiarity with techniques in FISH and CMA.
• Familiarity with high throughput DNA sequencing (also called next generation sequencing).
• Desired Qualifications:
  • Participation in scholarly activities.