Oncology Regional Business Director - Northeast

Summit Therapeutics Inc. is a biopharmaceutical oncology company focused on improving quality of life, increasing potential duration of life, and addressing serious unmet medical needs. Our core values include integrity, passion for excellence, purposeful urgency, collaboration, and commitment to people. Summit is currently conducting multiple global Phase 3 clinical studies in oncology, including:

• Non-small Cell Lung Cancer (NSCLC):
  • HARMONi: Phase 3 study evaluating ivonescimab combined with chemotherapy vs. placebo plus chemotherapy in EGFR-mutated, locally advanced or metastatic non-squamous NSCLC (previously treated with a 3rd generation EGFR TKI).
  • HARMONi-3: Phase 3 study evaluating ivonescimab combined with chemotherapy vs. pembrolizumab combined with chemotherapy in first-line metastatic NSCLC.
  • HARMONi-7: Phase 3 study evaluating ivonescimab monotherapy vs. pembrolizumab monotherapy in first-line metastatic NSCLC.
• Colorectal Cancer (CRC):
  • HARMONi-GI3: Phase 3 study evaluating ivonescimab in combination with chemotherapy vs. bevacizumab plus chemotherapy.

Ivonescimab is an investigational therapy not presently approved by any regulatory authority other than China’s National Medical Products Administration (NMPA). Summit is headquartered in Miami, Florida, with additional offices in California, New Jersey, the UK, and Ireland.

About the role

The Regional Business Director (RBD) will lead the successful launch and commercialization of ivonescimab within an assigned U.S. region. Reporting to the Head of U.S. Sales, the RBD is responsible for executing national sales strategies, leading a high-performing team of oncology account managers, and driving regional performance to achieve commercial objectives.

Responsibilities

• Execute national sales strategies and business plans to achieve regional sales objectives and market share goals.
• Recruit, develop, coach, and retain a high-performing team of oncology account managers, fostering a culture of accountability, collaboration, and excellence.
• Lead regional launch readiness and execution, ensuring sales representatives are prepared to effectively promote ivonescimab and deliver a best-in-class customer experience.
• Monitor regional sales performance through KPIs, performance metrics, and business analytics; provide ongoing coaching and development to maximize team effectiveness.
• Develop strategic regional business plans and account strategies to optimize customer engagement and resource deployment.
• Partner closely with Marketing, Medical Affairs, Market Access, Commercial Operations, and other cross-functional teams to ensure aligned execution of commercial initiatives.
• Build and maintain strong relationships with key oncology customers, healthcare systems, and regional stakeholders.
• Gather and communicate customer insights, competitive intelligence, and market dynamics to inform commercial strategy and continuous improvement.
• Lead regional sales meetings, business reviews, and field coaching activities to reinforce strategic priorities and share best practices.
• Ensure all commercial activities are conducted in compliance with company policies, industry regulations, and applicable legal requirements.
• Manage regional travel, expenses, and resources responsibly.
• Perform all other duties as assigned.

Requirements

• Bachelor's degree in business, life sciences, or a related field; advanced degree preferred.
• Minimum of 10+ years of pharmaceutical or biotechnology sales experience, including 5+ years of oncology sales leadership experience.
• Recent experience leading or supporting oncology product launches; NSCLC experience strongly preferred.
• Demonstrated success leading and developing high-performing oncology sales teams.
• Strong coaching, leadership, and performance management skills.
• Proven ability to analyze sales data and translate insights into actionable business plans.
• Excellent communication, presentation, and relationship-building skills.
• Experience collaborating effectively with cross-functional commercial and medical teams.
• Strong understanding of the oncology marketplace, customer landscape, and account-based selling.
• Ability to travel up to 75%, including overnight travel, based on business needs.

Pay

$215,000 - $240,000 USD. Actual compensation packages are based on several factors unique to each candidate, including skill set, depth of experience, certifications, and specific work location. This may differ in other locations due to differences in the cost of labor. The total compensation package may also include bonus, stock, benefits, and/or other applicable variable compensation.