Manager Manufacturing Solution Prep - Nights

Join Amgen’s mission of serving patients. At Amgen, our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With a focus on four therapeutic areas—Oncology, Inflammation, General Medicine, and Rare Disease—we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions.

About the role

In this vital role, you will champion a safe and compliant production environment through structured on-the-floor presence. You will drive problem-solving and continuous improvement among the team and collaborate with cross-functional partners in Quality, EHSS, F&E, and Process Development. As an active player in our OnePlant operating model, you will build reliability, agility, and efficiency through our I-530 pathway and Agile Workforce.

The Front-Line Manager will collaborate routinely with Quality Assurance, Quality Control, Engineering, Facilities and Engineering, Maintenance, Process Development, Process Engineering, Supply Chain, Regulatory Compliance, and other site functions. This role requires strong technical ownership of manufacturing operations, disciplined execution of cGMP and safety expectations, and the ability to make timely decisions in a dynamic production environment.

The on-boarding phase for this role will last 2-6 weeks, during which time you will be on an administrative schedule (Monday through Friday, approximately 8am to 5pm). Following the on-boarding phase, you will join a shift team working a 12-hour shift (7pm - 7am, C or D shift) with a two-week rotation covering 7 days per week. The rotating shift offers an average of 14 days on shift per month with every other weekend off and a 15% shift differential.

Responsibilities

• Safety and Quality Oversight: Reinforce a strong safety and quality culture within the shift, ensuring standards are upheld through active engagement and coaching.
• Operational Leadership: Lead the shift and collaborate with peer managers to reliably deliver production targets. Coordinate daily task allocation and plan ahead with the scheduling team for short- to mid-term schedule needs. Provide Purposeful Presence on the Floor (Gemba) to monitor overall department performance, provide coaching, and ensure consistency with core Floor Operating Principles.
• Coordinate with support functions to troubleshoot, identify, and resolve issues while on shift.
• Talent Development: Mentor and develop talent, fostering an environment of engagement, belonging, continuous learning, and operational excellence. Build a high-performing team, ensuring accountability and advancing technical and leadership capabilities.
• Continuous Improvement, Innovation, and Process Enhancement: Identify and drive process improvement initiatives to support higher efficiency and eliminate non-value-added activities.
• Agile Workforce Leadership: Role model ARI Manufacturing’s Agile Workforce behaviors by planning and executing cross-training and dynamic resource allocation across AR5 and AR30 to enhance responsiveness and productivity while increasing opportunities for staff development.
• Leading Strategy Development and Execution: Assist in developing and implementing departmental strategy and plans aligned with broader AR5, ARI, and site manufacturing objectives. Translate strategic priorities into clear daily, weekly, and shift-level execution plans. Anticipate operational, quality, safety, training, and schedule risks and build contingencies to reduce impact.
• Deliver strong business results through continuous improvement, standardization, and disciplined execution. Use metrics, audit outcomes, process data, and staff feedback to identify trends and improve performance. Lead change efforts that improve safety, compliance, quality, efficiency, throughput, and reliability.
• Ensure the team understands how daily execution connects to Amgen’s mission, patient impact, and AR5 business priorities.
• Building a Strong Organizational Alignment: Be responsible for selection, onboarding, training, evaluation, staff relations, performance management, and development of manufacturing staff. Ensure the right people, skills, and resources are in place and optimally allocated to achieve production, quality, and business goals.
• Interact with management to optimize organizational structure, roles, responsibilities, and shift performance. Build and develop a diverse, impactful team that can reliably execute complex manufacturing operations. Work across functions to build organizational and individual capability.
• Develop strong relationships with staff members and provide open, clear, and actionable feedback. Foster a team environment that supports accountability, innovation, continuous improvement, learning, knowledge-sharing, and psychological safety.
• Promote clear communication across shifts to ensure continuity, alignment, and readiness. Lead with a people-centered approach that supports engagement, retention, empowerment, and development.

Requirements

• High school diploma / GED and 12 years of Manufacturing and Operations experience, or
• Associate’s degree and 10 years of Manufacturing and Operations experience, or
• Bachelor’s degree and 5 years of Manufacturing and Operations experience, or
• Master’s degree and 3 years of Manufacturing and Operations experience, or
• Doctorate degree

In addition to meeting at least one of the above requirements, you must have experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation of resources. Your managerial experience may run concurrently with the required technical experience referenced above.

Preferred Qualifications

• Background in Life Sciences or Engineering
• Knowledge and experience within a cGMP or other highly regulated environment, including a basic understanding of technical elements across engineering, biological, or chemical processing
• Skilled in change management, team building, and fostering innovation
• Excellent communication skills, drive, sense of urgency, and analytical problem-solving abilities
• Demonstrated experience in applying Operational Excellence and Lean Manufacturing
• Experience with performance management, including coaching, conflict resolution, and performance reviews
• Ability to be flexible and manage change
• Demonstrated ability to forge and maintain strong relationships with other functional areas
• User-level fluency with digital tools for daily management, data analysis and visualization, and application of Artificial Intelligence (e.g., Copilot, Chat GPT, etc.)

Benefits

From competitive benefits to a collaborative culture, we support your professional and personal growth and well-being. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted, with actual salary varying based on relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models, including remote and hybrid work arrangements, where possible

Schedule

• On-boarding phase: 2-6 weeks on an administrative schedule (Monday through Friday, approximately 8am to 5pm)
• Post on-boarding: 12-hour shift (7pm - 7am, C or D shift) with a two-week rotation covering 7 days per week
• Average of 14 days on shift per month with every other weekend off
• 15% shift differential