Ligand Binding Analytical Scientist II – Princeton, NJ

Job Responsibilities

• Performing ligand binding assays (e.g., ELISA, ECL, RIA, cell-based assays) in accordance with established methods, SOPs, and regulatory requirements.
• Sustaining method development, optimization, and validation activities for LBAs used to measure biomarkers, pharmacokinetics (PK), and immunogenicity.
• Processing and analyzing biological matrices (e.g., serum, plasma) using validated assay procedures.
• Operating key laboratory instruments and platforms such as MSD, ELISA readers, automated liquid handlers, and immunoassay systems.
• Identifying, troubleshooting, and resolving assay performance issues in collaboration with senior scientists.
• Documenting all laboratory activities with precision to ensure data integrity, traceability, and regulatory compliance.
• Reviewing raw data, performing data reduction, and ensuring data accuracy using specialized software applications.
• Contributing to the creation, review, and improvement of SOPs and technical documentation.
• Maintaining a clean, organized, and compliant laboratory environment, including equipment maintenance and waste handling.
• Supporting general laboratory operations to ensure seamless daily workflow.

Qualifications

• A Bachelor’s degree in Biology, Biochemistry, Immunology, or another relevant scientific discipline.
• Hands-on laboratory experience with ligand binding assays (ELISA, ECL, or related platforms).
• Understanding of bioanalytical processes and regulated laboratory environments.
• Experience using analytical software and strong proficiency in MS Excel and Word.
• Familiarity with immunoassay platforms such as MSD or similar systems (strong plus).
• Experience working under GxP or other regulated frameworks.
• Strong attention to detail, analytical thinking, and a collaborative work style.