Histocompatibility Technologist

About the role

Vanderbilt Health, with eight hospitals and over 180 clinics, is the region’s largest comprehensive academic health system, dedicated to moving medicine forward through preeminent programs in patient care, education, and research. The Histocompatibility & Immunogenetics team performs high‑complexity histocompatibility testing—including molecular typing, antibody monitoring, and flow cytometry—for transplant, disease association, and drug resistance/susceptibility. This role offers the opportunity to make a meaningful impact within a leading transplant program, working alongside highly skilled professionals in a fast‑paced, rewarding environment.

Responsibilities

• Perform HLA typing using molecular methods per SOPs and protocols.
• Analyze and interpret HLA alleles and haplotype frequencies.
• Isolate lymphocytes from peripheral blood, spleen, and lymph nodes.
• Conduct cellular‑based antibody screening by flow cytometry crossmatch and perform initial analysis.
• Perform antibody screening and specificity analysis using Luminex solid‑phase methods, with initial analysis.
• Generate initial crossmatch and antibody screening reports for manager/director review.
• Combine HLA typing, flow crossmatch, and antibody screening results to draft the Virtual Crossmatch Report for final director review.
• Receive requests from transplant coordinators and physicians and forward them to the laboratory manager/director.
• Perform additional duties as assigned.

Qualifications

• Certification: Histocompatibility Technologist – American College of Histocompatibility and Immunogenetics (ACHI).
• Work experience: Relevant experience; less than 1 year acceptable.
• Education: Bachelor’s degree.

Benefits

Comprehensive benefits package that may include health, disability, retirement, and wellness offerings to support well‑being and professional growth.

Pay

Competitive third‑shift differential.

Schedule

Overnight (third) shift schedule.