Jobs · Analyst · California

Founding Bioinformatics Engineer

Novaflow (YC S25) · San Francisco, CA · 3 mo ago
On-siteAnalyst$100k–$150k/yrFull-time

About the role

The Founding Bioinformatics Engineer will build and maintain bioinformatics pipelines for genomics, transcriptomics, and other -omics data. This includes writing clean, reproducible analysis code in Python and/or R, setting up and managing cloud infrastructure, integrating existing tools, validating pipeline outputs, and collaborating with academic labs and data partners.

Responsibilities

  • Build and maintain bioinformatics pipelines for genomics, transcriptomics, and other -omics data
  • Write clean, reproducible analysis code in Python and/or R
  • Set up and manage cloud infrastructure (AWS or GCP) for large-scale compute workloads
  • Integrate existing bioinformatics tools, databases, and data sources into the platform
  • Validate pipeline outputs against published methodologies and real scientific standards
  • Work with academic labs, tool providers, and data partners to expand what the platform can do
  • Help decide what we build next based on what researchers actually need

Requirements

  • Bachelor's or Master's in Computational Biology, Bioinformatics, Biomedical Engineering, or a related field (PhD is a plus)
  • 2+ years building bioinformatics pipelines or computational biology workflows
  • Strong in Python and/or R
  • Know your way around bioinformatics file formats (FASTQ, BAM, VCF, HDF5, etc.)
  • Experience running workloads on AWS or GCP
  • Comfortable in Linux/Unix command-line environments
  • Solid understanding of molecular biology (genomics, gene expression, variant calling)
  • Good communicator who can work across biology and engineering
  • Experience with Nextflow, Snakemake, or similar workflow managers
  • Docker experience
  • Familiarity with LLMs or AI/ML tools
  • Experience across multiple biomedical domains
  • Startup or biotech/pharma background
  • Previous startup experience (prior experience either working for or founding a startup)

Qualifications

  • Experience with Nextflow, Snakemake, or similar workflow managers
  • Docker experience
  • Familiarity with LLMs or AI/ML tools
  • Experience across multiple biomedical domains
  • Startup or biotech/pharma background
  • Previous startup experience (prior experience either working for or founding a startup)

Skills

  • Python
  • R
  • Linux/Unix command-line environments
  • Bioinformatics file formats (FASTQ, BAM, VCF, HDF5, etc.)
  • Cloud infrastructure (AWS or GCP)
  • Workflow managers (Nextflow, Snakemake)
  • Docker
  • LLMs or AI/ML tools
  • Molecular biology (genomics, gene expression, variant calling)

Benefits

  • Competitive salary and meaningful equity as a founding team member
  • 401(k) with company match
  • Unlimited PTO + federal holidays
  • Monthly health and wellness stipend
  • Meals covered when you're in the office (lunch daily, dinner when you're working late)
  • Team offsites and company events

Pay

$100K - $150K

Schedule

Full-time

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