Founding Bioinformatics Engineer
Novaflow (YC S25) · San Francisco, CA · 3 mo ago
On-siteAnalyst$100k–$150k/yrFull-time
About the role
The Founding Bioinformatics Engineer will build and maintain bioinformatics pipelines for genomics, transcriptomics, and other -omics data. This includes writing clean, reproducible analysis code in Python and/or R, setting up and managing cloud infrastructure, integrating existing tools, validating pipeline outputs, and collaborating with academic labs and data partners.
Responsibilities
- Build and maintain bioinformatics pipelines for genomics, transcriptomics, and other -omics data
- Write clean, reproducible analysis code in Python and/or R
- Set up and manage cloud infrastructure (AWS or GCP) for large-scale compute workloads
- Integrate existing bioinformatics tools, databases, and data sources into the platform
- Validate pipeline outputs against published methodologies and real scientific standards
- Work with academic labs, tool providers, and data partners to expand what the platform can do
- Help decide what we build next based on what researchers actually need
Requirements
- Bachelor's or Master's in Computational Biology, Bioinformatics, Biomedical Engineering, or a related field (PhD is a plus)
- 2+ years building bioinformatics pipelines or computational biology workflows
- Strong in Python and/or R
- Know your way around bioinformatics file formats (FASTQ, BAM, VCF, HDF5, etc.)
- Experience running workloads on AWS or GCP
- Comfortable in Linux/Unix command-line environments
- Solid understanding of molecular biology (genomics, gene expression, variant calling)
- Good communicator who can work across biology and engineering
- Experience with Nextflow, Snakemake, or similar workflow managers
- Docker experience
- Familiarity with LLMs or AI/ML tools
- Experience across multiple biomedical domains
- Startup or biotech/pharma background
- Previous startup experience (prior experience either working for or founding a startup)
Qualifications
- Experience with Nextflow, Snakemake, or similar workflow managers
- Docker experience
- Familiarity with LLMs or AI/ML tools
- Experience across multiple biomedical domains
- Startup or biotech/pharma background
- Previous startup experience (prior experience either working for or founding a startup)
Skills
- Python
- R
- Linux/Unix command-line environments
- Bioinformatics file formats (FASTQ, BAM, VCF, HDF5, etc.)
- Cloud infrastructure (AWS or GCP)
- Workflow managers (Nextflow, Snakemake)
- Docker
- LLMs or AI/ML tools
- Molecular biology (genomics, gene expression, variant calling)
Benefits
- Competitive salary and meaningful equity as a founding team member
- 401(k) with company match
- Unlimited PTO + federal holidays
- Monthly health and wellness stipend
- Meals covered when you're in the office (lunch daily, dinner when you're working late)
- Team offsites and company events
Pay
$100K - $150K
Schedule
Full-time