FDA Postdoctoral Fellowship in Mechanistic Studies of Male Reproductive Toxicity

About the role

The FDA Postdoctoral Fellowship in Mechanistic Studies of Male Reproductive Toxicity is embedded within a multidisciplinary research program at NCTR's Division of Biochemical Toxicology. This fellowship investigates the mechanistic basis of cannabidiol (CBD)-induced male reproductive toxicity in mice, directly supporting FDA's regulatory evaluation of CBD-containing products.

Responsibilities

• Collect and analyze RNA sequencing data using bioinformatics pipelines for differential gene expression and pathway enrichment analysis.
• Contribute to the generation and analysis of liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based internal dosimetry data.
• Collaborate in spatial distribution analyses using matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-MSI).
• Collaborate with a multidisciplinary team of biologists, analytical chemists, pathologists, biostatisticians, and regulatory scientists from CDER.
• Present research findings to federal stakeholders, including FDA and NIEHS, and at national scientific conferences.
• Contribute to peer-reviewed manuscripts and scientific reports.
• Gain experience with public data deposition practices that reinforce FDA's commitment to transparency and open science.

Requirements

The candidate should be currently pursuing or have received a doctoral degree in a relevant field. The degree must have been received within the past five years, or is anticipated to be received by the appointment start date. The candidate should be a U.S. citizen or have lived in the United States for at least 36 out of the past 60 months.

Qualifications

The candidate should have a strong background in toxicology, bioinformatics, and molecular biology. Experience with RNA sequencing, LC-MS/MS, and MALDI-MSI is preferred.

Skills

Strong skills in programming (R, Python, etc.), data analysis, and scientific writing are essential. Excellent communication and collaboration skills are also required.

Benefits

The participant will receive a monthly stipend commensurate with educational level and experience. Proof of health insurance is required for participation in this program.

Pay

The participant will receive a monthly stipend commensurate with educational level and experience.

Schedule

The appointment will initially be for one year, but may be renewed upon recommendation of FDA and is contingent on the availability of funds.