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Jobs · OTHR · Arkansas

FDA Postdoctoral Fellowship - Hepatotoxicity in New Approach Methodologies

Oak Ridge Institute for Science and Education · Jefferson, AR · 2 wk ago
OTHRFull-time

Research Project

You will contribute to a project investigating the performance of established and emerging liver toxicity biomarkers in two New Approach Methodology (NAM) platforms, including liver microtissues and liver-on-a-chip systems. The objective of this project is to develop translational biomarkers that can be reliably measured in NAMs to predict chemical-induced liver toxicity in humans.

Learning Objectives

  • Train to culture primary human liver cells using NAM platforms
  • Treat cells with chemicals at human-relevant concentrations
  • Assess liver toxicity using biochemical assays of enzyme activities
  • Communicate research outcomes with regulatory agencies
  • Learn about biomarker and NAM qualification processes
  • Gain experience conducting research within a regulatory agency

Mentor

The mentor for this opportunity is Qiang Shi (Qiang.Shi@fda.hhs.gov).

Application Requirements

  • An application
  • Transcripts – Click here for detailed information about acceptable transcripts
  • A current resume/CV, including academic history, employment history, relevant experiences, and publication list
  • One educational or professional recommendation

Contact Information

If you have questions, send an email to ORISE.FDA.NCTR@orau.org. Please include the reference code for this opportunity in your email.

Location and Duration

  • FDA Office and Location: FDA Office and Location: A research opportunity is available immediately with the Food and Drug Administration (FDA), The National Center for Toxicological Research (NCTR) located in Jefferson, Arkansas.
  • Appointment Length: The appointment will initially be for two years, but may be renewed upon recommendation of FDA and is contingent on the availability of funds.

Citizenship Requirements

  • This opportunity is available to U.S. citizens, Lawful Permanent Residents (LPR), and foreign nationals.
  • Non-U.S. citizen applicants should refer to the Guidelines for Non-U.S. Citizens Details page of the program website for information about the valid immigration statuses that are acceptable for program participation.

Background Investigation

All applicants must complete a successful background investigation by the Office of Personnel Management before being on-boarded at FDA.

Stipend and Insurance

  • Participant will receive a monthly stipend commensurate with educational level and experience.
  • Proof of health insurance is required for participation in this program.

Qualification Requirements

  • Currently pursuing or have received a doctoral degree in one of the relevant fields.
  • Discipline(s): Chemistry and Materials Sciences (12 ), Communications and Graphics Design (2 ), Computer, Information, and Data Sciences (17 ), Earth and Geosciences (21 ), Engineering (29 ), Environmental and Marine Sciences (14 ), Life Health and Medical Sciences (51 ), Mathematics and Statistics (11 ), Physics (16 ), Science & Engineering-related (2 ), Social and Behavioral Sciences (29 )
  • U.S. citizen, or have lived in the United States for at least 36 out of the past 60 months.

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