Executive Medical Director, Medical Strategy (Hepatologist)

Key Responsibilities

• Serve as a senior Hepatology clinical and scientific subject-matter expert in MASH and related metabolic liver diseases, providing authoritative medical guidance to internal and external stakeholders.
• Inform and help shape global medical strategies by contributing deep clinical insight and scientific interpretation within the strategic framework established by Global Medical Strategy leadership.
• Partner with senior leaders across Global Medical Affairs, R&D, and HEOR to identify critical evidence gaps and drive meaningful data generation.
• Act as a senior medical advisor to Commercial and Market Access teams, providing scientific guidance on initiatives requiring medical expertise, in compliance with all regulations.
• Build and maintain relationships with top thought leaders (TLs), partnering with MSLs to manage strategic engagements and scientific collaborations.
• Participate in Corporate Advisory Panels ensuring strategic alignment with company-wide initiatives

Medical Affairs Research and Evidence Generation

• Provide senior medical expertise and strategic input for Phase 4 and post-approval studies, in collaboration with Clinical Development leadership.
• Serve as a key medical advisor to HEOR, ensuring scientific relevance and credibility.
• Collaborate with HEOR and Clinical Development to define and execute a prioritized real-world evidence agenda.
• Serve as a core member of the Publication Strategy Review Team (PSRT) to ensure scientific integrity and medical accuracy.
• Support execution of the global Investigator-Initiated Study (IIS) strategy and governance processes, providing medical review and strategic input as requested.

Cross-Functional and Operational Integration

• Contribute to the training of field medical teams to ensure scientific accuracy and consistency.
• Provide clinical mentorship and continuous development to enhance scientific acumen and engagement capabilities.
• Contribute to critical product and portfolio decisions that inform the strategic direction of Madrigal’s medical and scientific initiatives.
• Contribute clinical and scientific expertise to asset-level decision-making.
• Provide strategic and scientific review for content, ensuring medical accuracy and relevance across materials and channels.
• Review and provide input on Custom and Standard Response Medical Information documents, ensuring consistency with the latest scientific evidence.
• Engage as a strategic advisor or member of the Brand Team, providing input into brand strategy and ensuring scientific alignment.

Field Medical and Scientific Excellence

• Contribute to the training of field medical teams to ensure scientific accuracy and consistency.
• Provide clinical mentorship and continuous development to enhance scientific acumen and engagement capabilities.

Organizational Leadership and Talent Development

• Foster a culture of scientific excellence, collaboration, and continuous improvement within Global Medical Affairs.
• Ensure all activities comply with company SOPs, industry standards, and applicable regulations.
• Uphold the highest ethical standards in all external engagements.

Travel Requirement

Ability to travel up to 25% for key leadership meetings, congresses, corporate locations, and stakeholder engagement.

Required & Desired Qualifications

• Hepatologist (MD/DO or equivalent) with clinical experience in MASH
• 15+ years pharmaceutical (or related) industry experience
• Deep knowledge of the changing US healthcare environment
• Excellent interpersonal and communication skills (written and oral)
• Possess a strong scientific/clinical acumen
• Possess a thorough understanding of all US compliance guidelines relevant to the pharmaceutical industry and field medical roles
• Highly ethical and with strong compliance record
• Ability to manage others through change, demonstrating poise under pressure and motivational leadership

Company Benefits

• Base salary is determined by several factors including the candidate’s qualifications, skills, education, experience, business needs and market demands.
• Full-time employees receive equity, which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create.
• Comprehensive benefits, including flexible paid time off, medical, dental, vision and life/disability insurance, and 401(k) offerings (i.e., traditional, Roth, and employer match).
• Additional voluntary benefits like supplemental life insurance, legal services, and other offerings.
• Mental health benefits through our Employee Assistance Program for employees and their family.

Equal Opportunity Employer

We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance, please contact HR@madrigalpharma.com.

Unsolicited Resumes

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