Senior Director, Therapeutic Area (Hepatology)

About the role

Senior Director Therapeutic Area (Hepatology)- US- Remote
ICON plc is a world-leading healthcare intelligence and clinical research organization. We're proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.

Key Responsibilities

• Lead strategic Hepatology drug development program design, delivering tailored, asset-focused solutions across liver diseases including MASLD/MASH, alcohol-associated liver disease (ALD), cirrhosis, viral hepatitis, and other chronic and rare liver conditions like PBC, PSC, PFIC
• Own end-to-end protocol development, including design, scientific review, and evaluation for Hepatology clinical trials across Phases I-IV
• Partner directly with senior client stakeholders (e.g., CMO, TA Heads, Clinical Development leadership) to provide expert guidance on Hepatology development strategy and data interpretation
• Act as scientific and strategic lead in proposal development, study strategy, and bid defense activities within Hepatology
• Build and maintain strong relationships with Hepatology key opinion leaders (KOLs), advisory boards, and relevant regulatory authorities
• Contribute to the development of Hepatology-focused service offerings, supporting innovation and growth in liver disease drug development capabilities
• Provide training, mentorship, and thought leadership in Hepatology to internal teams and external partners
• Participate in portfolio reviews, governance discussions, and scientific oversight of Hepatology programs
• Support operational teams with high-level scientific input, including investigator meetings and Hepatology-specific study discussions
• Represent the organization at Hepatology congresses and scientific forums to promote clinical excellence and scientific leadership

What You Bring

• Deep, recognized expertise in Hepatology and liver disease drug development
• Strong understanding of Hepatology clinical trial design, biomarkers, endpoints (e.g., fibrosis staging, histologic and non-invasive markers), and evolving therapeutic landscapes (e.g., MASLD/MASH, alcohol-associated liver disease (ALD), cirrhosis, immuno-Hepatology approaches and antiviral therapies)
• Proven ability to operate in a strategic, client-facing, consultative environment within pharmaceutical or clinical research settings
• Experience engaging and influencing senior scientific and clinical stakeholders across industry and academia
• Excellent communication and presentation skills, with the ability to translate complex Hepatology data into clear, actionable development insights
• Collaborative, global mindset with strong cross-functional leadership capability
• MD required, ideally with specialization or substantial clinical/research experience in Hepatology

Additional Information

• 20- 40% travel (domestic and international)
• Opportunity to work in a highly visible, impact-driven role shaping the future of Hepatology drug development