Director, Translational Medicine, Imaging

Responsibilities

• Develop translational strategies designed to support clinical development plans, the regulatory path, and product commercialization.
• Lead the development and implementation of translational imaging strategies in support of clinical proof-of-mechanism, patient stratification, dose selection.
• Serve as the neuroimaging lead on cross-functional program teams.
• Partner with Research to discover and characterize novel imaging biomarkers in preclinical studies.
• Develop imaging methods and analytically validate imaging tools for clinical use.
• Implement clinical biomarkers and ensure biomarker-driven decision-making across all phases of drug development.
• Lead cross-functional imaging governance (e.g., Imaging Steering Committee) advancing the use of imaging biomarkers to enable demonstration of disease-modifying effects.
• Oversee CRO vendor/partners ensuring that they optimally execute clinical and preclinical imaging projects in the US, Canada, and other regions of interest.
• Provide support for the Business Development organizations as needed on diligence efforts.

Requirements

• PhD, MD, PharmD, or equivalent degree in Neuroscience, Biomedical Imaging, Radiology, or related discipline.
• 6+ years of industry experience in translational medicine, imaging sciences, or clinical development.
• Deep expertise in clinical and translational neuroimaging, including MRI and PET methodologies.
• Must have direct experience managing imaging protocols in the conduct of clinical trials (endpoints, inter-site harmonization, imaging core lab oversight, etc.).
• Specific experience with imaging endpoints for early-stage clinical development in CNS, ophthalmic and inflammatory diseases is desired.

Benefits

The estimated compensation range for this position is $ 203,000.00 - $ 215,100.00 per year.

Pay

The estimated compensation range for this position is $ 203,000.00 - $ 215,100.00 per year.

Schedule

The position is based in Cambridge, Massachusetts.