Director/Sr. Director Clinical Pharmacology

For our client, we are seeking a Director/Sr. Director Clinical Pharmacology to join the team of a leader in the Pharmaceuticals & Biotech space. This role will shape clinical pharmacology strategy across pediatric development programs, with a strong emphasis on quantitative decision-making and model-informed drug development. The Director/Sr. Director will partner closely with clinical, regulatory, and development teams to guide dose selection, study design, and overall program execution. The position also plays a key role in translating complex pharmacometric findings into regulatory-ready insights, publications, and scientific presentations. Location: Remote - US based candidates only, no visa sponsorship available Compensation: $262,800 – $284,800 annually Responsibilities Develop and implement clinical pharmacology and pharmacometrics strategies for pediatric drug development programs Manage the design and application of population PK, PK/PD, and PBPK models for decision-making Conduct analyses to support study design, dose selection, and efficacy/safety optimization in pediatric trials Author and contribute to clinical pharmacology sections of regulatory documents for submissions Design clinical pharmacology studies and oversee execution, including management of CROs and vendors Apply quantitative tools for early development decisions and first-in-human study design Present results and contribute to scientific publications and conference presentations Qualifications Ph.D. or Pharm.D. in a relevant field with 10+ years of experience in the biotech/pharmaceutical industry Hands-on experience with modeling and simulation related to drug development, especially pediatrics Expertise in population PK, PK/PD, mechanistic modeling (PBPK), and quantitative data analysis Proficiency with pharmacometrics tools and programming languages such as NONMEM and R Strong understanding of global regulatory expectations for clinical pharmacology and model-informed drug development (MIDD) Excellent analytical and critical thinking skills to translate quantitative data into actionable insights Strong communication skills, including the ability to present findings to diverse audiences Benefits Comprehensive health benefits, including 100% employer-paid premiums for you and your dependents 401(k) with employer match and an employee stock purchase program (ESPP) Flexible work model with hybrid options and generous paid time off Strong focus on employee development through education and professional growth opportunities Subsidized lunch program and pre-tax commuter benefits for on-site work days Our client is an equal opportunity employer. We encourage you to apply even if you don’t meet every qualification—your background could be exactly what this team needs.