Director, Protein Sciences

About the role

Johnson & Johnson is seeking a Director, Protein Sciences for a hybrid role based in Spring House, PA or Cambridge, MA. This position represents a critical function within a dynamic Biologics Discovery organization committed to delivering next-generation biotherapeutics to patients.

Responsibilities

• Lead evaluation of therapeutic targets, including structural, sequence, and domain architecture analysis
• Integrate internal and external data (literature, databases, structural repositories)
• Define antigen and engineered-cell design strategies to support antibody discovery
• Construct design and domain selection
• Epitope exposure and conformational state optimization
• Strategies for difficult targets (e.g., multi-pass membrane proteins) including Nanodisc technology and nucleic acid immunogen design
• Contribute to multiple aspects of antibody discovery in a globally-integrated research environment
• Drive impact across a diverse portfolio of innovative drug concepts
• Operate effectively within a highly coordinated, fast-paced environment
• Contribute both strategically and hands-on to program advancement

Qualifications

• A minimum of a Ph.D. in Biochemistry, Structural Biology, Protein Engineering, or a related discipline
• A minimum of 10 years of experience in biologics discovery or protein sciences
• Demonstrated leadership experience within the pharmaceutical or biotech industry
• Strong knowledge in antigen design and generation for antibody discovery; structural biology and protein sequence analysis; biologics discovery workflows from target to lead identification
• Experience or domain knowledge in Oncology, Immunology, and/or Neuroscience
• People management experience preferred
• Excellent verbal and written communication skills
• Strategic with a strong scientific mindset
• The ability to operate effectively within a highly coordinated, fast-paced matrix environment

Preferred Skills

• Analytical Reasoning
• Biochemistry
• Business Savvy
• Chemistry
• Manufacturing, and Control (CMC)
• Clinical Research and Regulations
• Clinical Trial Designs
• Compliance Management
• Developing Others
• Drug Discovery Development
• Inclusive Leadership
• Leadership
• Molecular Diagnostics
• Operational Excellence
• Pharmacovigilance
• Process Improvements
• Productivity Planning
• Product Strategies
• Program Management
• Scientific Research
• Stakeholder Management

Pay

The anticipated base pay range for this position is: $164,000.00 - $282,900.00

Benefits

• Consolidated Retirement Plan (pension)
• Savings Plan (401(k))
• Long-term incentive program
• Vacation – 120 hours per calendar year
• Sick time – 40 hours per calendar year; 48 hours for employees in the State of Colorado; 56 hours for employees in the State of Washington
• Holiday pay, including Floating Holidays – 13 days per calendar year
• Work, Personal and Family Time – up to 40 hours per calendar year
• Bereavement Leave – 240 hours for an immediate family member; 40 hours for an extended family member per calendar year
• Caregiver Leave – 80 hours in a 52-week rolling period
• Volunteer Leave – 32 hours per calendar year
• Military Spouse Time-Off – 80 hours per calendar year

Additional Description

For Pay Transparency Subject to the terms of their respective plans, employees are eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)). This position is eligible to participate in the Company’s long-term incentive program.