Director, Program Management

About the role

We're looking for a Director, Program Management on the Program Management team to help us expand what's possible for patients with serious and rare diseases. Reporting to the Executive Director, Research & Respiratory Disease Program Management, you'll serve as a trusted strategic advisor and operational backbone of the Global Program Team (GPT), enabling the Global Program Head (GPH) to lead with strategic focus while ensuring disciplined, integrated execution across the full program lifecycle - from development through regulatory submission, manufacturing, and commercial launch.

Responsibilities

• Support the GPH in defining and executing integrated Program strategy, ensuring alignment between GPT priorities, functional plans, and corporate/portfolio objectives
• Facilitate GPT meetings and ongoing team effectiveness, including working norms, decision rights, cadence, and communication pathways
• Define and manage critical path activities, integrated timelines, resource plans, and program budgets across all functions
• Lead the development and maintenance of key program documentation including Target Product Profiles (TPPs), Integrated Development Plans (IDPs), and Integrated Evidence Plans (IEPs), dashboards, and risk assessments
• Oversee Life Cycle Management (LCM) activities and Health Authority submissions (IND, NDA, JNDA, MAA, BLA) in coordination with Regulatory Affairs
• Maintain decision logs, risk registers, and version-controlled program records, ensuring visibility of key metrics and outcomes across the GPT
• Aid in drafting and co-creating Executive Committee (EC) materials and facilitating key program governance meetings
• Partner with the PM team and global organization to design new processes and supporting business structures, recommending solutions that drive process standardization and simplification
• Challenge the organization to be innovative, make it safe to try new approaches, and take prudent risks; coach teams to learn from setbacks and drive continuous improvement

Requirements

• Proven track record of leading drug programs from early development through commercialization, including regulatory submissions (NDA, BLA, MAA, IND) and product launches
• Experience working within or alongside Global Program Teams (GPTs) or equivalent cross-functional program structures in a Program-First or matrix operating model
• Background in rare disease, respiratory, or specialty therapeutics preferred, consistent with Insmed's pipeline focus
• Experience with commercial launch preparation and cross-functional readiness planning is a strong plus
• Proficiency in program management tools: MS Project, Smartsheet, Veeva, SharePoint, Excel, PowerPoint
• Entrepreneurial, self-starter with a results-oriented work ethic and a positive, can-do attitude in fast-paced, high-stakes environments

Qualifications

• Bachelor's degree in a scientific, medical, or business discipline
• 12+ years of progressive Program/Project Management experience in a biotech or biopharmaceutical environment

Skills

• Strong leadership and strategic thinking skills
• Excellent communication and facilitation skills
• Ability to manage complex projects and prioritize tasks effectively
• Experience with regulatory affairs and Health Authority interactions
• Strong analytical and problem-solving skills
• Ability to manage multiple projects simultaneously

Benefits

Insmed offers comprehensive medical, dental, and vision coverage and mental health support, annual wellbeing reimbursement, and access to our Employee Assistance Program (EAP). Generous paid time off policies, fertility and family-forming benefits, caregiver support, and flexible work schedules with purposeful in-person collaboration are also provided. The company also offers a 401(k) plan with a competitive company match, annual equity awards, and participation in our Employee Stock Purchase Plan (ESPP), and company-paid life and disability insurance.

Pay

$177,000.00-242,000.00 Annual

Schedule

This is a hybrid role based out of our Bridgewater, NJ office. You’ll have the option to work remotely most of the time, with in-person collaboration when it matters most.

Travel

This position involves frequent domestic & international travel (up to 20%).

Equal Opportunity Employer

Insmed is an Equal Opportunity employer. We do not discriminate in hiring on the basis of physical or mental disability, protected veteran status, or any other characteristic protected by federal, state, or local law. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.