Director, Oncology Research

Director, Oncology Research

Let’s do this. Let’s change the world. Amgen is a leader in the discovery and development of innovative cancer therapeutics. The Oncology Research team seeks a Director of Research to develop and lead a portfolio of antibody-based therapeutics for solid tumors. In this role, you will work cross-functionally to implement and advance next-generation approaches for cancer therapeutics.

• Lead preclinical research for T-cell engager clinical programs and external collaborations, focused on lung and neuroendocrine cancer.
• Build and lead a portfolio of innovative research programs focused on bispecific antibodies.
• Mentor a team of project leaders and lab-based scientists to discover new biology, deliver robust datasets and make critical decisions for therapeutic programs and technology platforms.
• Contribute to the identification and evaluation of external research opportunities, including business development partnerships and academic collaborations.
• Partner effectively with peers across research and development to advance new science and integrate technology with tumor cell biology, including application of AI/ML approaches to target evaluation and biomarker discovery.

What We Expect Of You

• A dynamic professional with these qualifications:
  • Doctorate degree in Cancer Biology, Cell Biology, Genetics, or related field [and relevant post-doc where applicable] and 5 years of directly related experience OR
  • Master’s degree in Cancer Biology, Cell Biology, Genetics, or related field and 8 years of directly related experience OR
  • Bachelor’s degree in Cancer Biology, Cell Biology, Genetics, or related field and 10 years of directly related experience
• Deep understanding of lung cancer biology.
• Direct experience leading T-cell engager research programs from target identification and validation to clinical candidate selection and submission of IND/CTA.
• Demonstrated understanding of preclinical dataset required for development candidate nomination, and experience interacting with regulatory authorities, preferred.
• Knowledge of antibody engineering approaches, with direct experience designing and evaluating modalities including T-cell engagers and antibody-drug conjugates.
• Experience developing translational biology datasets and interpreting clinical biomarker data.
• Demonstrated ability to use AI/ML to accelerate research and translational biology.

What You Can Expect Of Us

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan.
• Stock-based long-term incentives.
• Award-winning time-off plans.
• Flexible work models where possible.

Pay & Benefits

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

Application Instructions

Apply now and make a lasting impact with the Amgen team. careers.amgen.com