Director, Oncology Research
BioSpace · South San Francisco, CA · 6 days ago
HealthcareFull-time
Responsibilities
- Lead preclinical research for T-cell engager clinical programs and external collaborations, focused on lung and neuroendocrine cancer.
- Build and lead a portfolio of innovative research programs focused on bispecific antibodies.
- Mentor a team of project leaders and lab-based scientists to discover new biology, deliver robust datasets and make critical decisions for therapeutic programs and technology platforms.
- Contribute to the identification and evaluation of external research opportunities, including business development partnerships and academic collaborations.
- Partner effectively with peers across research and development to advance new science and integrate technology with tumor cell biology, including application of AI/ML approaches to target evaluation and biomarker discovery.
Qualifications
- Doctorate degree in Cancer Biology, Cell Biology, Genetics, or related field [and relevant post-doc where applicable] and 5 years of directly related experience
- OR Masters degree in Cancer Biology, Cell Biology, Genetics, or related field and 8 years of directly related experience
- OR Bachelors degree in Cancer Biology, Cell Biology, Genetics, or related field and 10 years of directly related experience
- Deep understanding of lung cancer biology.
- Direct experience leading T-cell engager research programs from target identification and validation to clinical candidate selection and submission of IND/CTA.
- Demonstrated understanding of preclinical dataset required for development candidate nomination, and experience interacting with regulatory authorities, preferred.
- Knowledge of antibody engineering approaches, with direct experience designing and evaluating modalities including T-cell engagers and antibody-drug conjugates.
- Experience developing translational biology datasets and interpreting clinical biomarker data.
- Demonstrated ability to use AI/ML to accelerate research and translational biology.
- Demonstrated high scientific impact through publications, invited talks and patents.