Director, Medical Science Liaison - Epilepsies

The Opportunity

The Opportunity

Primary Responsibilities

• Lead, coach, and develop a high-performing team of epilepsy MSLs, setting clear objectives, performance expectations, and individual development plans
• Build and scale a high-performing Field Medical organization, including workforce planning, succession planning, talent assessment, onboarding strategy, and capability development
• Establish field medical operating standards, performance expectations, and excellence frameworks to ensure consistent execution and scientific credibility across the team
• Lead territory design, resource allocation, and organizational planning to ensure optimal coverage of key centers, investigators, and stakeholders throughout pre-launch and launch
• Translate Medical Affairs strategy into an actionable field medical plan, including engagement priorities, scientific objectives, and team success metrics
• Oversee KOL and center engagement strategy, territory alignment, and account planning across priority academic and community neurology centers
• Ensure the team delivers accurate, balanced, and compliant scientific exchange on disease state, clinical data, and the relutrigine clinical profile in rare and genetic epilepsies
• Build team capability and readiness for pre-launch and launch, including onboarding, scientific training, and field coaching on SCN2A, SCN8A, and broader epilepsy populations
• Agregate, synthesize, and elevate field insights to inform medical, clinical, and commercial strategy, and report on field medical activity and impact
• Partner cross-functionally with internal Praxis leadership to ensure aligned execution
• Represent Field Medical Affairs at scientific congresses, advisory boards, and internal governance forums
• Manage field medical operations, including CRM utilization, metrics and reporting
• Establish, monitor, and enforce compliance with regulatory requirements, company policies, SOPs, and industry standards across all field activities
• Maintain current expertise in the rare epilepsy landscape, competitive environment, and evolving treatment paradigms, and ensure the team stays scientifically current

Qualifications and Key Success Factors

• Advanced clinical or scientific degree (PharmD, PhD, or MD; NP, PA, or RN with relevant experience)
• Substantial Medical Affairs / MSL experience in biotech or pharma, including demonstrated people-leadership or field-management experience
• Proven success leading geographically dispersed field medical teams, including experience managing managers and/or leading organizations through periods of growth, transformation, or launch
• Experience establishing field medical strategy and operating models in pre-launch and launch environments
• Demonstrated ability to influence senior executives and drive cross-functional alignment without direct authority
• Experience supporting Market Access initiatives, including Managed Care strategy, payer engagement, and reimbursement activities
• Experience managing budgets, headcount planning, and organizational resource allocation
• Strong scientific acumen with the ability to coach the team through complex clinical and data discussions in rare patient populations
• Demonstrated ability to translate medical strategy into field execution and measurable results
• Experience in neurology or CNS disorders required; rare or genetic epilepsy experience strongly preferred
• Product launch and pre-launch experience strongly preferred
• Excellent cross-functional leadership, influence, and communication skills
• Ability to manage competing priorities, budgets, and resources with strong organization and attention to detail
• Willingness to travel up to ~75%, including field co-travel, scientific congresses, and internal meetings

Compensation & Benefits

Annualized Base Salary: $230,000 - $250,000 USD

Company Overview

Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders. Our core Values of Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.

Diversity, Equity & Inclusion

Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.

Attention: Job Scam Alert

Praxis has recently become aware of fraudulent job recruitment postings from individuals claiming to represent Praxis. These postings seek financial information in connection with fraudulent opportunities for employment. If you suspect any fraudulent activity or misrepresentation in connection with a Praxis job opportunity, please report it to careers@praxismedicines.com.

Attention: Unsolicited Submissions

Praxis does not accept unsolicited submissions from recruitment agencies for open positions. We ask all recruitment agencies to refrain from contacting any Praxis employee regarding any position. All unsolicited resumes submitted by recruitment agencies to any Praxis employee in any form or method will be deemed to be the property of Praxis, and Praxis explicitly reserves the right to hire those candidate(s) without any financial obligation to the recruitment agency.