Clinical Research Project Manager B/C

This role encompasses two levels — Clinical Research Project Manager B and C — within the Perelman School of Medicine in Philadelphia, PA. Positions are contingent upon grant funding.

About the role

Clinical Research Project Manager B oversees complex clinical research projects with limited oversight from senior leadership. Coordinates multicenter studies, ensures adherence to protocols and SOPs, and develops quality assurance processes. Contributes to protocol and budget development, supervises project staff, and manages performance. Facilitates grant applications, stakeholder communication, and compliance with regulatory and institutional requirements.

Clinical Research Project Manager C provides leadership for large and complex clinical research projects, guiding study strategy and operations across multiple domestic and international sites. Oversees project design, documentation, and compliance, and ensures quality data collection and reporting. Supervises project teams, manages grants and budgets, and leads dissemination of study results through publications and presentations. Builds collaborations with external partners and funding agencies.

Responsibilities

Clinical Research Project Manager B

• Manage single and/or multi-site clinical research projects (including study start up, daily operations, external site communications, recruitment and enrollment, and troubleshooting; quality assurance and quality control; study close out activities).
• Develop, create and review regulatory submission and study documents/tools, including protocols, consents, annual reports, source docs, training slides, manual of procedures, Data Safety Monitoring Board charter, clinical report forms, standard operating procedures.
• Provide assistance with Investigational New Drug, Investigational Device and Clinical Trial Agreement exemption determinations.
• Assist/conduct pre-award finance activities (medical record abstraction/medicare coverage analysis development, clinical trials management system registration, research billing number, driving contract timelines, budgeting input or development, grant writing assistance); and/or post award finance activities (invoicing, billing review).
• Staff supervision: Train direct and/or indirect research staff in program/division/dept procedures as required per protocol(s). Includes onboarding and training, data and lab management, protocol compliance and quality control/quality assurance, human subjects protection and good clinical practice, and project assignments/staff mentoring/biannual performance appraisal completion.
• Perform additional duties as assigned.

Clinical Research Project Manager C

• Manage mostly complex, multi-site clinical research projects (including study start up, daily operations, external site communications, recruitment and enrollment, and troubleshooting; quality assurance and quality control; study close out activities).
• Develop, create and review regulatory submission and study documents/tools, including protocols, consents, annual reports, source docs, training slides, manual of procedures, Data Safety Monitoring Board charter, clinical report form, standard operating procedure.
• Provide assistance with investigational new drug, investigational device and clinical trial agreement exemption determinations.
• Assist/conduct pre-award finance activities (medical record abstraction/medical coverage analysis development, registration, research billing number, driving contract timelines, budgeting input or development, grant writing assistance); and/or post award finance activities (invoicing, billing review).
• Staff supervision: Assist and train direct and/or indirect research staff in program/division/dept procedures as required per protocol(s). Includes onboarding and training, data and lab management, protocol compliance and quality control/quality assurance, human subjects protection and good clinical practice, and project assignments/staff mentoring/bi-annual performance appraisal completion.
• Perform additional duties as assigned.

Qualifications

Clinical Research Project Manager B

• Bachelor's Degree with 5–7 years of related experience or equivalent combination of education and experience (required).
• Master's degree and 3–5 years of experience (preferred).

Clinical Research Project Manager C

• Bachelor's Degree with 7–10 years of related experience or equivalent combination of education and experience (required).
• Master's degree and 5–7 years of experience (preferred).

Pay

Annual salary range: $91,066.00 – $117,901.00. Salary offers are made based on the candidate’s qualifications, experience, skills, and education as they directly relate to the requirements of the position, and in alignment with salary ranges based on external market data for the job’s level. Internal organization and peer data at Penn are also considered.

Benefits

• Health, Life, and Flexible Spending Accounts: Comprehensive medical, prescription, behavioral health, dental, vision, and life insurance benefits; flexible spending accounts for eligible health care and dependent care expenses with pre-tax dollars.
• Tuition: Tuition assistance for employee, spouse, and dependent children at Penn; dependent children also eligible for tuition assistance at other institutions.
• Retirement: Generous retirement plans (Basic, Matching, and Supplemental) with pre-tax or Roth options; investment options through TIAA and Vanguard.
• Time Away from Work: Substantial paid time off for vacation, personal affairs, illness, family care, and recovery.
• Long-Term Care Insurance: Offered in partnership with Genworth Financial for faculty, staff, and eligible family members; no proof of good health required for newly hired employees.
• Wellness and Work-life Resources: Wide variety of programs and resources to support health, family, and work-life balance.
• Professional and Personal Development: Array of resources for personal and professional advancement.
• University Resources: Access to libraries, athletic facilities, arboretum, art galleries, museums, cultural events (e.g., Penn Museum, Annenberg Center, Penn Relays), many free for employees and families.
• Discounts and Special Services: Discounts on arts/entertainment, transportation, mortgages, cellular plans, movie tickets, theme parks, and vehicles from Ford and General Motors.
• Flexible Work Hours: Non-traditional work hours, locations, and/or job structures to promote work-life balance.
• Penn Home Ownership Services: Forgivable loan for eligible employees buying a home or residing in West Philadelphia, usable for closing costs or home improvements.
• Adoption Assistance: Reimbursement of qualified expenses (travel, court fees) for up to two adoptions per household.

Background checks may be required after a conditional job offer; consideration will be tailored to the job requirements.