Clinical Operations Lead (+ Equity) at fast-growing venture-backed biotech startup

About the role

Fast-growing venture-backed biotech startup. This pivotal founding role involves building a clinical operations function from scratch to execute end-to-end trials. You will lead protocol development, site initiation, and regulatory submissions while driving efficiency through modernized workflows. It’s a hands-on opportunity to redefine traditional trial structures within a high-growth environment focused on speed and technical excellence. Build and own the entire clinical operations function from the ground up at an early-stage company. Backed by top-tier VCs, this role offers significant equity and the ability to influence core company strategy. Operates with a lean, high-velocity culture that prioritizes smart execution over standard industry bureaucracy. Location: San Francisco, USA.

Responsibilities

• Direct end-to-end trial management including protocol authoring, site qualification, and vendor contracting for global programs.
• Implement and optimize modernized operational workflows to accelerate timelines without compromising regulatory compliance or data integrity.
• Manage essential documents and regulatory submissions while coordinating directly with sites to ensure high-quality data collection.

Requirements

• Deep experience running clinical trials from protocol to database lock with minimal infrastructure and a hands-on approach.
• Proven ability to navigate complex international regulatory environments and manage sites in diverse global markets effectively.
• A tech-forward mindset with experience implementing innovative tools to automate manual processes and increase operational efficiency.