Biology Research Scientist (BA, MS, PhD)
Weekday AI (YC W21) · United States · 1 wk ago
RemoteRemoteOTHR$50–$70/hrPart-time
Key Responsibilities
- Review scientific publications, patents, and other primary literature to verify protein target assignments against UniProt records
- Evaluate the accuracy of protein annotations in large-scale bioactivity databases using scientific evidence
- Identify, categorize, and document incorrect target assignments using established validation guidelines
- Recommend the correct UniProt accession numbers where annotation discrepancies are identified
- Prepare concise, evidence-based summaries that clearly explain scientific reasoning and validation decisions
- Collaborate with research teams to improve the quality and reliability of biological datasets used in AI applications
Required Qualifications
- Bachelor's degree with 5+ years of relevant industry experience
- Master's degree with 2+ years of relevant industry experience
- PhD with research or industry experience in biotechnology, pharmaceutical sciences, or drug discovery
- Education in Pharmacology, Biochemistry, Molecular Biology, Chemical Biology, or a closely related life sciences discipline
- Hands-on experience with binding or functional assays such as: SPR, TR-FRET, Radioligand Binding Assays, Kinase Assays, GPCR Functional Assays, IC50, Ki, or KD measurements
- Currently working in a laboratory or research environment as a Scientist, Associate Scientist, or equivalent research role
- Practical experience using UniProt or related workflows supporting: Structure-Activity Relationship (SAR), High-Throughput Screening (HTS), Target Validation, Biochemical Profiling, IND-Enabling Research
Preferred Qualifications
- Experience working with bioactivity databases such as ChEMBL, BindingDB, or PubChem
- Knowledge of selectivity profiling and counterscreening methodologies
- Understanding of pharmacological distinctions such as agonists vs. antagonists and activators vs. inhibitors
- Strong literature review, analytical reasoning, and scientific documentation skills
- Excellent written communication with exceptional attention to detail