Biologist (Mass Spectrometry)

Overview

Axle is a bioscience and information technology company that advances translational research, biomedical informatics, and data‑science applications for research centers and healthcare organizations worldwide. The team includes experts in biomedical science, software engineering, and program management, and works with leading research institutions such as multiple NIH institutes.

Responsibilities

• Perform a range of analytical development activities in support of the characterization and quantification of biologic products, including vaccines, monoclonal antibodies, recombinant proteins, and other biologic modalities.
• Utilize mass spectrometry for characterization and quantification of biologic molecules in support of vaccine and other biologics development programs.
• Perform and support LC‑MS–based analytical testing, including sample preparation, data acquisition, data analysis, interpretation, and documentation of results.
• Execute established analytical methods and contribute to the development, optimization, qualification, troubleshooting, and transfer of new or existing analytical methods.
• Analyze and interpret experimental data using sound scientific judgment; identify trends, technical issues, and unexpected results and contribute to investigations and troubleshooting activities.
• Support the Bioseparations function within Analytical Development by performing electrophoresis‑based analytical techniques for the separation and characterization of biologic molecules.
• Work independently on assigned laboratory activities while collaborating with senior scientists and other members of multidisciplinary project teams.
• Maintain accurate, complete, and detailed experimental records and prepare technical documentation, summaries, and presentations of analytical results.
• Effectively communicate experimental results, technical observations, and potential issues to project teams and participate in internal scientific and project meetings.
• Support multiple development projects and effectively prioritize assigned laboratory activities to meet project timelines.
• Contribute to continuous improvement of analytical workflows and identify opportunities to improve assay performance, robustness, efficiency, and data quality.
• Work collaboratively across Analytical Development and with other functional groups within the Vaccine Production Program to support project objectives.

Requirements

• Ph.D. in mass spectrometry, analytical chemistry, biochemistry, chemistry, pharmaceutical sciences, or a related scientific discipline with 1–2 years of relevant pharmaceutical or biotechnology industry experience applying mass spectrometry to characterize biomolecules; OR a Master’s degree in a related discipline with 4–5 years of relevant industry experience.
• Hands‑on experience with mass spectrometry and LC‑MS–based analytical techniques for analysis of biologic molecules.
• Experience with quantitative and/or qualitative analytical methods used for characterization of proteins, antibodies, vaccines, or other biologic products.
• Experience with electrophoresis‑based analytical techniques for protein/biologic separation and characterization (preferred).
• Working knowledge of analytical method development, optimization, troubleshooting, and data interpretation.
• Demonstrated ability to work independently, exercise scientific judgment, troubleshoot experimental issues, and proactively communicate findings.
• Self‑starter, independent thinker, and effective team player capable of collaborating with cross‑functional groups.
• Strong record‑keeping and scientific documentation skills.
• Excellent analytical, problem‑solving, organizational, oral, and written communication abilities.
• Ability to manage multiple assignments and priorities in a fast‑paced R&D laboratory environment.
• Familiarity with computer software used for scientific data acquisition, analysis, visualization, documentation, and presentation.

Benefits

• 100% Medical, Dental & Vision coverage for employees
• Paid Time Off (including holidays)
• Employee Referral Bonus
• 401(k) match
• Tuition reimbursement and professional development opportunities
• Flexible Spending Accounts: Healthcare (FSA)
• Parking Reimbursement Account (PRK)
• Dependent Care Assistance Program (DCAP)
• Transportation Reimbursement Account (TRN)

Pay

Market‑competitive salary with an anticipated base compensation range of $95,000 USD – $110,000 USD, varying by experience, qualifications, skills, and location.