Associate Scientist II, Drug Metabolism and Distribution

Responsibilities

• Perform routine tasks competently and independently and generate reliable and consistent results.
• Lab based position in a high functioning analytical laboratory.
• Ability to perform in vitro assays and routinely work with radio labeled compounds.
• Optimize procedures and protocols to enhance productivity and efficiency with input from a more senior scientist.
• Competently perform all sample preparation for analysis (LC, MS, Scintillation).
• Independently operate LC and MS instruments to collect data for both Discovery and Development studies across multiple vendor platforms (Thermo, Sciex).
• Learn and understand new experimental techniques.
• Appropriately modify protocols, as required, to suit the changing needs of research or development sciences.
• Build theoretical and practical knowledge to carry out job function.
• Place data in proper scientific context by consulting and citing relevant literature.
• Demonstrate technical proficiency in his/her field.
• Impact projects predominantly through lab-based activities.
• Demonstrate proficiency by learning multiple experimental techniques.
• General understanding of drug metabolism and disposition in drug discovery and development.
• Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drugs and radioactive compounds, GxP compliance, and animal care where applicable.
• Show good oral and written communication skills.
• Routinely present data clearly and thoroughly in both one-on-one and group meetings with clear and precise graphs/charts/tables.
• Provide written summary reports as appropriate.
• Ability to communicate group objectives outside of DMD.
• Exhibit a strong willingness to learn and contribute as a team player with a positive attitude.
• Learn and share knowledge with colleagues and participate in internal and external presentation opportunities.
• Plan and perform routine tasks competently and independently within a timely fashion, and generate reliable and consistent results.
• Documentation of experimental activities and results in a GMP compliant fashion using an electronic data acquisition and management system.
• Analyze and critique results, noting significant deviations from the expected results.
• Troubleshoot experiments and instrumentation.
• Learn and understand new experimental techniques with a curiosity to apply them for unique project/assignment requirements.
• Demonstrate skill in multiple techniques and appropriately modify protocols, as required, to suit the changing needs of research or development sciences.
• Demonstrate technical proficiency in his/her field, preferentially in the analytical areas of quantitative and instrumental analysis.
• Impact projects predominantly through lab and/or pilot plant based activities.
• Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drugs and radioactive compounds, and GxP compliance, where applicable.

Qualifications

• Bachelor's Degree in Chemistry, Analytical Chemistry, or equivalent education, with typically 3 or more years experience or Masters Degree or equivalent education (no additional experience).
• Theoretical and practical knowledge and experience (in chromatography and / or mass spectrometry) is highly preferred to carry out job function.
• Excellent oral and communication skills.