Associate Scientist II, AD

About the role

Forge Biologics is seeking an Associate Scientist II, Analytical Development (Protein-Based Assays) to support the development and optimization of protein-based assays for AAV gene therapy products. This position is responsible for executing complex protein-based assays, contributing to method development, and collaborating with cross-functional teams to ensure the quality and consistency of our AAV gene therapy products. This role offers an excellent opportunity to gain hands-on experience in the critical analytical aspects of gene therapy development.

About us

At Forge Biologics, we believe in turning bold ideas into life-changing realities. Our mission is to enable access to life-changing gene therapies and help bring them from ideas into reality. We partner with scientists, physicians, biotech and pharma innovators, and patient communities — all united by one goal: improving lives.

Our team works out of The Hearth, a state-of-the-art, 200,000-square-foot cGMP facility in Columbus, Ohio. Here, you’ll be part of a culture of H.O.P.E.: Hardworking, Open, Purpose-driven, and Engaged. We are committed to helping you expand your skills, take on new challenges, and develop your career through mentorship, hands-on learning, and opportunities for advancement.

Responsibilities

• Lead the execution of complex protein-based assays independently and troubleshoot technical issues.
• Develop and optimize protein-based assays, including assay design, protocol development, and validation.
• Collaborate with scientists to analyze and interpret experimental data.
• Mentor and provide guidance to junior team members.
• Contribute to assay transfer activities between teams or sites.
• Participate in project planning and ensure timely delivery of results.
• Assist in the preparation of regulatory documents and support regulatory submissions.
• Stay current with industry trends and incorporate best practices into assay development.
• Implement quality control measures to ensure the reliability and robustness of assays.
• Actively engage in continuous improvement efforts for processes and methodologies.

Requirements

• Bachelor's or Master's degree in a relevant scientific field (e.g., biology, biochemistry, molecular biology).
• Proficiency in advanced laboratory techniques related to protein-based assays.
• Experience with assay development and optimization.
• Ability to troubleshoot technical issues and recommend solutions.
• Strong data analysis skills and the ability to generate actionable insights from experimental results.

Work Environment and Physical Demands

This position works in both a laboratory environment and typical office environment where the physical work demands will vary depending on the specific tasks required. The employee will be stationary (standing/sitting) for extended periods of time. Employees regularly wear personal protective equipment based on the task being performed. Must be able to work in a confined space, such as a clean room or laboratory environment. Ability to identify small details within the field of vision, distinguish between different colors, and accurately identify objects within a specific area.

Benefits

• Health, dental, and vision insurance starting your first day, with 90% of premiums covered for you and your family.
• Competitive paid time off plan.
• 12 weeks of fully paid parental leave.
• Annual bonus opportunities for all full-time team members.
• 401(k) with company match.
• Special employee discounts, including childcare and dependent care savings.
• Onsite fitness facility at The Hearth.
• Mental health counseling and financial planning services through our Employee Assistance Program.
• Employer-paid short and long-term disability coverage.
• Fully stocked kitchen with free snacks and beverages.
• Ongoing professional development resources, training, and mentorship programs.