Associate Scientist – Drug Formulation

About the role

We're seeking an Associate Scientist on the Drug Formulation team to help expand possibilities for patients with serious diseases. Reporting to the Senior Scientist, you'll focus on developing, optimizing, and characterizing nanoparticle-based drug delivery systems. You'll join a multidisciplinary team working on non-viral vehicle formulation and characterization, supporting platform build and project-level activities.

Responsibilities

• Contribute to the advancement of RNA/gene-based therapeutic programs through hands-on formulation science and rigorous analytical evaluation.
• Work on formulation and characterization of lipid nanoparticles (LNPs) and other nanoparticle-based delivery systems for platform development and project support.
• Design and execute formulation studies, including nucleic acid encapsulation into nanoparticle systems, analytical testing, and stability evaluations to finalize formulation compositions for RNA/gene-based therapies.
• Perform comprehensive physicochemical characterization of nanoparticle formulations, including size, polydispersity index (PDI), surface charge (zeta potential), encapsulation efficiency, drug loading, and release kinetics.
• Apply a broad set of analytical techniques such as Dynamic Light Scattering (DLS), Nanoparticle Tracking Analysis (NTA), UV-Vis spectroscopy, Size Exclusion Chromatography (SEC), SDS-PAGE, HPLC, and fluorescence-based assays to evaluate nanoparticles and drug products.
• Synthesize and develop nanoparticle-based formulations for various therapeutic areas.
• Characterize and evaluate bioconjugates, including physicochemical properties, stability, conjugation efficiency, and binding ability.
• Collaborate with team members to troubleshoot formulation challenges and propose data-driven solutions.
• Perform data and statistical analyses using Excel and GraphPad Prism.
• Maintain accurate, detailed, and timely records in electronic notebooks and generate internal technical reports.

Requirements

• A BS/MS degree with 2+ years of experience in Pharmaceutics, Chemistry, Biomedical Engineering, Chemical Engineering, or a related field.
• Hands-on experience in nanoparticle-based formulation development and analytical characterization.
• Prior work with nucleic acid delivery systems, especially lipid-based or polymeric nanoparticles.
• Experience with nucleic acid encapsulation techniques.
• Experience with bioconjugate and targeted delivery.
• Proficient in physicochemical and biochemical characterization techniques, including: Dynamic Light Scattering (DLS), Nanoparticle Tracking Analysis (NTA), Size Exclusion Chromatography (SEC), UV-Vis Spectroscopy, HPLC, SDS-PAGE, Fluorescence-based assays, protein quantification methods.
• Strong data analysis and interpretation skills using GraphPad Prism, Excel, or similar tools.
• Familiarity with stability testing, release profiling, and formulation optimization.
• Demonstrated ability to independently design, execute, interpret, and present experimental results.
• Experience in data processing, analysis, statistics, and data interpretation.