Associate Scientist - Bioanalysis

About the role

The Senior Scientist will join the bioanalysis team to support nonclinical studies for Orna Therapeutics' diverse programs. The role is 100% lab-based and involves developing and implementing ligand binding assays (LBA) and PCR assays, performing sample testing, and presenting results to the pre-clinical team.

Responsibilities

• Tissue processing from mice, rat, and NHP in vivo studies for RNA and protein extraction.
• Independently implement LBA and qPCR to measure large molecules such as protein and RNA from plasma and tissues samples.
• Perform method development and troubleshooting on LBA and qPCR-based assays with guidance.
• Provide high-quality bioanalytical support focusing on PK, TK, and PD assessments.
• Deliver and present experimental results to the pre-clinical team.
• Maintain detailed experimental protocols and electronic laboratory notebooks.

Requirements

• BS with 0-4+ years of related industrial or academia experience, or MS with 0-2+ years of related industrial or academia experience in biology, chemistry, pharmaceutical science, or related fields.
• Major in biology, chemistry, pharmaceutical science or related fields.
• Authorized to work in the United States on a full-time basis.

Qualifications

• Experience and knowledge in RT-QPCR, ddPCR, bDNA, and Ligand binding assay.
• Experience with Ligand binding assays on Luminex and MSD platforms.
• Experience in tissue sample processing is a plus.

Skills & Preferences

• Basic understanding of data analysis using Excel and GraphPad Prism.