Associate Scientist - Analytical & Bioanalytical Mass Spectrometry (ABMS)

About the role

Regeneron Pharmaceutical's Analytical and Biological Mass Spectrometry Group (ABMS), located in Tarrytown, NY, is seeking a motivated Associate Scientist to join a fast-paced, interdisciplinary team working on analytical and bioanalytical development for novel siRNA/oligonucleotide-based modalities in a diverse genetic medicine pipeline.

Responsibilities

• Develop and optimize liquid chromatography coupled to mass spectrometry (LC-MS) related methods for the enrichment, detection, quantification, and structural characterization of siRNAs, oligonucleotides, novel siRNA conjugates, and monoclonal antibodies (mAbs).
• Perform analytical testing and sample preparation of siRNA/oligonucleotides with a focus on chromatographic fractionation, LC, LC-MS, solid phase extraction (SPE), hybridization-capture, and other mass spectrometry related methods.
• Independently conduct sample preparation and LC-MS analyses in compliance with SOPs or drafted protocols, and document experimental procedures and results in an electronic laboratory notebook (ELN).

Requirements

• BS or MS degree in Chemistry, Biochemistry, Pharmaceutical Sciences, or a related field with 0–3 years of relevant hands-on laboratory experience in analytical chemistry or bioanalytical sciences.
• Strong hands-on experience with liquid chromatography (such as reversed-phase, size-exclusion, ion exchange chromatography), particularly HPLC or UPLC techniques.
• Hands-on experience with various types of biological matrices is a plus.
• Hands-on experience with fractionation, solid phase extraction, and/or hybridization techniques is particularly valuable.
• While mass spectrometry experience is beneficial, we prioritize candidates with excellent chromatography skills and the ability to optimize separation methods.
• Comfortable working independently after initial guidance and able to communicate effectively about technical challenges and results.

Qualities we value

• Mentally flexible and adapt quickly to changing priorities in a fast-paced environment.
• Excellent team player who can follow directions while also bringing your own insights to problem-solving.
• Growth mindset and eagerness to embrace new challenges and learning opportunities.
• Interest in learning about genetic medicines and development for impactful RNA-based therapies.

Pay

Salary Range (annually): $70,300.00 – $110,100.00

Benefits

Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role:

• Annual bonuses or other incentive plans.
• Equity awards.
• Pension or retirement benefits, 401(k) company match.
• Health and wellness programs, fitness centers.
• Insurance benefits (e.g., medical, dental, vision, life, and disability).
• Paid time off and family support benefits.

For additional information about Regeneron benefits in the U.S., visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.

Schedule

This role is required to be performed onsite. Please speak with your recruiter and hiring manager for more information about onsite expectations for your role and location.