Associate Director, Engineering and Materials Science

for prose. We need to parse the job description. General Summary: paragraph. Key Duties And Responsibilities: list of duties (multiple sentences). Should be turned into

• each duty. Knowledge And Skills: list of items (experience coaching/mentoring..., knowledge of..., ability to..., application..., experience..., strong communication...). Should be
  • . Education And Experience: paragraph (maybe bullet? It's a sentence). Could be

    . Pay Range: $169,600 - $254,400 plus mention of bonus, equity, overtime. That's pay info. Should be a Pay section with

    maybe. Benefits: description of benefits: inclusive market-leading benefits, medical/dental/vision, generous PTO, educational assistance, commuting subsidy, matching charitable donations, 401(k), etc. Should be Benefits section with

    • . Schedule: Flex designation: On-Site designated role, work five days per week on-site with ad hoc flexibility. That's schedule info. Should be Schedule section with

      . We must not include sections with placeholder like "commensurate with experience". Not present. We must not include duplicated lines. Remove boilerplate: EEO, E-Verify, accommodations, etc. Also remove "Company Information" maybe? It includes description of Vertex as global biotech etc. That's substantive? Might be considered company info but not required? The instruction: preserve ALL substantive information; do NOT invent or summarize away detail. The company info is substantive? It's about Vertex being a global biotech company etc. Might be considered boilerplate? It's not EEO/legal. It's a brief description. Could keep as a short paragraph maybe under "About the company" but we don't have a heading for that unless we create a section. The allowed headings list includes About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule. No "About the company". So we should not create a heading not in list. So we should omit that paragraph if it doesn't fit allowed headings. The instruction: Use

      for section headings (e.g. About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule). It says e.g., meaning those are examples, but we should prefer those headings. Likely we should only use those headings. So we can omit company info. Also "At Vertex, we embrace continuous learning..." that's about culture, could be part of About the role? Might be considered substantive but not fitting a heading. Could be included under About the role as prose. The "General Summary" could be About the role. So we can put that under

      About the role

      with

      . Responsibilities: Key Duties And Responsibilities ->

      Responsibilities

      with
      • . Requirements: Knowledge And Skills maybe under Requirements or Skills. The heading list includes Requirements, Qualifications, Skills. We have Knowledge And Skills (skills). Could put under

        Skills

        with
        • . Or Requirements. We'll choose Skills. Education And Experience: Could be under

          Qualifications

          with

          . Pay:

          Pay

          with

          . Benefits:

          Benefits

          with
          • . Schedule:

            Schedule

            with

            . We must not include any other headings. Now extract content. General Summary paragraph: "Vertex is seeking a talented individual to join the Engineering and Materials Science (EMS) department in Boston, MA. The successful candidate will be productive, results-oriented, and able to lead a diverse team of engineers and scientists to contribute to the successful development and scale-up of drug substance processes. Excellent interpersonal and organization skills as well as a high level of technical aptitude and creativity are required for success in this position." We'll put that as

            . Responsibilities: list each duty sentence. From text: "Responsible for leading and developing a cross-functional team of engineers and scientists in defining, developing, and demonstrating viable, multi-step syntheses for the robust manufacture of small-molecule or oligonucleotide active pharmaceutical ingredients, spanning all phases of clinical development through to commercialization and launch" "Lead drug substance process development efforts and apply sound scientific judgement to drive multiple assets in a fast-paced environment via laboratory development, modeling, drug supply preparation, and technology transfer to third party manufacturing facilities" "Collaborate with materials development, process chemistry, analytical development, and formulation groups to improve the overall development paradigm for definition and optimization of drug substance properties and performance across the clinical development spectrum." "Key member of the cross-functional modeling Community of Excellence to promote the adoption of process modeling within the department and more broadly across Pharmaceutical Sciences (PS). Potentially act as the EMS lead for a project" "Maintain a strong external presence and promote innovation. Be vested in developing team members and technically mentoring junior-level scientists." "As a member of the EMS leadership team, influence the delivery of technical excellence and the department strategy. Potentially lead an EMS or PS strategic initiative" "Use excellent communication and interpersonal skills to influence stakeholders and interact, lead, and collaborate within an interdisciplinary team comprised of chemical engineers, organic, physical, and analytical chemists, materials and solid-state scientists, and formulation development personnel" We'll make each a

          • . Knowledge And Skills (Skills): "Experience coaching/mentoring junior-level scientists" "Knowledge of standard unit operations encountered in small molecule and/or Oligonucleotide drug substance process development inclusive of particle engineering, reaction kinetics, thermodynamics, and transport fundamentals" "Ability to identify and solve complex process development and/or scale up problems" "Application of modeling to complex, physicochemical systems, data analysis, and statistical design of experiments" "Experience with process development and problem solving in a matrix environment" "Strong communication skills and the ability to influence both stakeholders and team members" We'll list each as
          • . Education And Experience (Qualifications): "BS Degree with 11+ MS Degree with 9+ or PhD with 6+ years experience in Chemical Engineering or a closely related field with relevant pharmaceutical experience" That's a bit weirdly phrased but we keep as is. Pay: "Pay Range $169,600 - $254,400 Disclosure Statement The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law." We'll put as

            . Benefits: "At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more." We'll split into list items maybe each benefit: medical, dental, vision; generous PTO (including week-long shutdown summer/winter); educational assistance programs including student loan repayment; generous commuting subsidy; matching charitable donations; 401(k); plus inclusive market-leading benefits etc. We'll just make each distinct benefit as

          • . Could also keep as prose but instruction: Use
            • for any list of duties/requirements/benefits. So we need to make a list. We'll extract benefits: - inclusive market-leading benefits to meet employees wherever they are in career, financial, family and wellbeing journey while providing flexibility and resources to support growth and aspirations - medical, dental and vision benefits - generous paid time off (including a week-long company shutdown in the Summer and the Winter) - educational assistance programs including student loan repayment - generous commuting subsidy - matching charitable donations - 401(k) - and so much more (maybe we can omit vague "and so much more"). We'll include the concrete ones. Schedule: "Flex Designation On-Site Designated Flex Eligibility Status In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time." We'll put as

              . Now produce HTML fragment. We must not include any extra text outside HTML. Let's craft:

              About the role

              Vertex is seeking a talented individual to join the Engineering and Materials Science (EMS) department in Boston, MA. The successful candidate will be productive, results-oriented, and able to lead a diverse team of engineers and scientists to contribute to the successful development and scale-up of drug substance processes. Excellent interpersonal and organization skills as well as a high level of technical aptitude and creativity are required for success in this position.

              Responsibilities

              • Responsible for leading and developing a cross-functional team of engineers and scientists in defining, developing, and demonstrating viable, multi-step syntheses for the robust manufacture of small-molecule or oligonucleotide active pharmaceutical ingredients, spanning all phases of clinical development through to commercialization and launch
              • Lead drug substance process development efforts and apply sound scientific judgement to drive multiple assets in a fast-paced environment via laboratory development, modeling, drug supply preparation, and technology transfer to third party manufacturing facilities
              • Collaborate with materials development, process chemistry, analytical development, and formulation groups to improve the overall development paradigm for definition and optimization of drug substance properties and performance across the clinical development spectrum.
              • Key member of the cross-functional modeling Community of Excellence to promote the adoption of process modeling within the department and more broadly across Pharmaceutical Sciences (PS). Potentially act as the EMS lead for a project
              • Maintain a strong external presence and promote innovation. Be vested in developing team members and technically mentoring junior-level scientists.
              • As a member of the EMS leadership team, influence the delivery of technical excellence and the department strategy. Potentially lead an EMS or PS strategic initiative
              • Use excellent communication and interpersonal skills to influence stakeholders and interact, lead, and collaborate within an interdisciplinary team comprised of chemical engineers, organic, physical, and analytical chemists, materials and solid-state scientists, and formulation development personnel

              Skills

              • Experience coaching/mentoring junior-level scientists
              • Knowledge of standard unit operations encountered in small molecule and/or Oligonucleotide drug substance process development inclusive of particle engineering, reaction kinetics, thermodynamics, and transport fundamentals
              • Ability to identify and solve complex process development and/or scale up problems
              • Application of modeling to complex, physicochemical systems, data analysis, and statistical design of experiments
              • Experience with process development and problem solving in a matrix environment
              • Strong communication skills and the ability to influence both stakeholders and team members

              Qualifications

              BS Degree with 11+ MS Degree with 9+ or PhD with 6+ years experience in Chemical Engineering or a closely related field with relevant pharmaceutical experience

              Pay

              Pay Range $169,600 - $254,400.