VP, U.S. Medical Affairs

Primary Responsibilities Include

• Deliver a highly effective U.S. medical launch that enables appropriate, evidence-based adoption
• Establish a credible and trusted Dyne scientific presence with U.S. KOLs, payers, and patient communities
• Build a scalable, high-performing Medical Affairs organization ready for multiple launches
• Effectively translate scientific and clinical data into strategies that drive both access and lifecycle value
• Establish foundational capabilities and ways of working in a first-launch environment

Enterprise & Launch Leadership

• Own U.S. medical strategy, launch readiness, and execution, with direct accountability for delivering multiple successful product launches from a medical affairs perspective
• Build and develop a strong leadership bench, establishing a leadership team capable of scaling with the organization and future launches
• Serve as a core member of cross-functional launch leadership, shaping enterprise decisions and influencing cross-functional tradeoffs, while resolving complex scientific, medical, and operational balance in a time-critical environment
• Ensure U.S. Medical Affairs capabilities, processes, governance, and resourcing are built and operationalized to support launch and early commercialization
• Represent U.S. Medical Affairs scientific priorities and business needs at the US LT and the GMA LT
• Drive culture intentionally during scale

U.S. Medical Affairs Strategy & Execution

• Define, own, and execute the U.S. Medical Affairs strategy aligned with global medical strategy and enterprise objectives
• Ensure aligned cross-functional strategies, goals, and execution in partnership with US LT
• Translate medical and clinical insights into actionable strategies that support appropriate product adoption, evidence generation, payer confidence, and long-term lifecycle value
• Oversee U.S. medical tactics, including KOL strategy, advisory boards, congresses, medical education, payer engagement, and scientific exchange

Organization Building & People Leadership

• Build, lead, and scale a best-in-class U.S. Medical Affairs organization, including Field Medical (Medical Science Liaisons and Medical Value Liaisons) and home-office medical functions, capable of operating with speed, rigor, and scientific credibility while delivering high impact outcomes in a first-launch setting and preparing for subsequent launches
• Establish clear goals, decision rights, accountability, and performance expectations across the organization
• Develop leadership bench strength, foster a culture of ownership and collaboration, and act as a role model for Dyne’s values during a period of rapid organizational growth
• Ensure comprehensive training and learning programs to continuously develop a high performing U.S. Medical Affairs organization

External Engagement & Scientific Leadership

• Serve as Dyne’s senior U.S. medical spokesperson to key external stakeholders, including clinical experts, academic leaders, payers, advocacy groups, and other partners
• Shape and optimize treatment paradigms through credible, compliant, and impactful scientific engagement
• Ensure high-quality, fair-balanced medical and scientific exchange across all U.S. external interactions
• Ensure real-time intelligence on competitive data and evolving treatment paradigm

Evidence Generation & Lifecycle Management

• Provide strategic oversight of U.S.-focused evidence generation, ensuring alignment with launch and lifecycle priorities
• Lead cross-functional alignment with Global Medical Affairs, Value & Access, and Clinical Development to ensure integrated evidence generation and launch execution
• Oversee the medical component of product lifecycle management, from launch through early commercialization

Medical Governance & Compliance

• Ensure the highest standards of medical integrity, compliance, and ethical conduct
• Maintain appropriate oversight of non-promotional and promotional medical review processes, ensuring scientific rigor and regulatory compliance while enabling timely launch execution
• Establish scalable medical governance frameworks appropriate for a newly commercial organization