VP, DM1 Commercial Asset Lead

Role Summary

The VP, DM1 Commercial Asset Lead (CAL) is a passionate driver of the value of Dyne’s DM1 commercial asset with a global perspective, bringing adaptable leadership to develop and implement commercialization strategies that maximize reach and value creation within the neuromuscular portfolio.

Primary Responsibilities Include

• Global Commercial Strategy & Asset Leadership

• Define global asset commercialization strategy and plan to achieve milestones and timelines for successful launches
• Shape competitive positioning, differentiation strategy, and overall value proposition
• Provide commercialization input into program strategy, including label and access considerations
• Establish strategic imperatives, critical success factors, and execution priorities

• Launch Readiness & Market Planning

• Lead global launch planning and readiness across key markets, starting with the U.S.
• Partner with cross-functional teams (medical, regulatory, supply, marketing, digital, data) to prepare for launch execution
• Collaborate with affiliate teams and external partners to support reimbursement and access readiness
• Drive continuous improvement and learning across markets

• Cross-Functional Leadership & Program Integration

• Serve as a key member of the Program Team and lead the DM1 Commercial Sub-Team
• Ensure alignment across commercialization pillars (product profile, access, launch planning)
• Facilitate cross-functional decision-making and drive timely outcomes
• Build strong partnerships across functions and maintain clear communication with leadership

• External Engagement & Stakeholder Management

• Build a credible and visible presence within the DM1 community, including KOLs, patient advocacy groups, and care teams
• Maintain awareness of competitive landscape and evolving market dynamics
• Support preparation and presentation of commercialization materials for senior leadership and Board discussions
• Participate in business development activities, including opportunity evaluation and due diligence, as needed

Qualifications

• Bachelor’s degree in a relevant scientific, medical, or business discipline required; advanced degree strongly preferred
• Minimum of 20 years of experience in the biopharmaceutical industry
• 15+ years of commercialization and cross-functional leadership experience
• Extensive experience leading global product launches, including a minimum of 3 launches
• Rare disease experience strongly preferred; neuromuscular experience highly advantageous
• Proven track record of delivering on business objectives in fast-paced, high-stakes environments
• Proven ability to steer assets from late-stage development through approval and launch
• Experience influencing global and U.S. market access and reimbursement readiness
• Demonstrated success developing global commercialization strategies
• Experience collaborating across clinical, medical, regulatory, supply, and commercial functions
• Ability to synthesize complex data to guide strategy
• Strong cross-functional leadership and stakeholder influence
• Proven ability to inspire and mobilize high-performing teams
• Exceptional communication and stakeholder engagement skills
• Ability to build strong external relationships (KOLs, advocacy, payers, regulators)
• Comfortable leading through ambiguity and change
• High integrity and strong patient-centric mindset
• Strong sense of urgency and ability to prioritize effectively