Vice President, Global Program Head - Neuroscience, Innovative Medicines

About the role

This is an enterprise-level executive role responsible for the end-to-end strategy, leadership, and delivery of the full portfolio within an assigned disease area, spanning multiple global programs from early development through regulatory approval and lifecycle management. The Global Program Head serves as the strategic owner of the disease-area portfolio and its assigned assets, driving a forward-looking, transformative vision grounded in scientific excellence, commercial insight, and patient impact. The role integrates scientific, clinical, regulatory, and commercial strategy to shape a differentiated portfolio, maximize asset value, and ensure successful progression throughout the product life cycle.

Position locations: hybrid role based near one of our hubs in West Chester PA USA, Parsippany NJ USA, Israel, or the Netherlands (relocation support is not available).

Responsibilities

• Strategic Leadership & Enterprise Vision
  • Set a bold, transformational asset vision anticipating future scientific, technological (e.g., AI, precision medicine), and market trends to increase program competitiveness.
  • Embrace accountability for strategic direction, value creation, integrated development planning, and long-term lifecycle management of the asset.
  • Synthesize complex internal and external insights, including the external competitive landscape, to inform enterprise-level decisions and scenario planning, ensuring a future-ready strategy despite ambiguity or evolving environments.
  • Uphold an enterprise mindset that prioritizes cross-functional alignment, shared purpose, and value delivery across R&D and commercial interfaces.
• End-to-End Program Ownership & Delivery
  • Own the full program lifecycle from preclinical stages through global approval and beyond, ensuring scientific rigor, regulatory readiness, and commercial differentiation.
  • Lead the Global Program Team (GPT) through major program governance interactions, including the Innovative Development Committee; represent the asset internally and externally to health authorities, advisory boards, and corporate partners.
  • Develop strong working relationships with all team members and functional stakeholders; cultivate a high-functioning partnership with the GPTD and with the commercial co-leader (late-phase programs).
• Stakeholder Leadership & External Engagement
  • Shape and align stakeholder expectations through transparent, evidence-based communication and inclusive decision-making.
  • Build and sustain trusted relationships with senior leaders, peers, team members, partners, external experts, and joint governance structures.
  • Navigate complex scientific, clinical, and organizational dynamics with diplomacy, influence, and tailored communication for diverse audiences.
• Global Program Team Leadership & Talent Development
  • Lead and inspire multidisciplinary global program teams, driving high performance, accountability, and shared ownership of outcomes.
  • Foster a “project first” approach within the GPT and inspire a “can-do” mindset; encourage risk-taking and bold ideas.
  • Partner with GPTD to ensure bold development plans with well-defined risk-balance and mitigations; account for interdependencies, operational readiness, and budgetary prudence.

Your Skills And Experience

• Minimum 15 years of experience in pharmaceutical/biotechnology R&D with demonstrated leadership across early and late development.
• Proven track record leading global, cross-functional teams without direct authority and delivering programs through major regulatory milestones (IND → Phase 3 → approval).
• Experience managing complex external partnerships, joint governance structures, and high-stakes program communication.
• Demonstrated deep scientific, clinical, regulatory, and commercial understanding across the development spectrum.
• Experience with lifecycle management and global submissions (NDA/BLA/MAA) is preferred.
• Doctoral degree (MD, PhD, PharmD) preferred.
• Experience with marketed products is preferred.
• Experience in Neuroscience and/or Immunology is preferred.

Competencies

• Enterprise Leadership: Elevates organizational thinking beyond functional priorities; inspires followership.
• Strategic Agility: Anticipates shifts in science, market, and technology; adjusts strategy proactively.
• Influence Without Authority: Builds alignment across senior stakeholders, resolves conflict, and enables decisive progress.
• Evidence-Based Decision-Making: Synthesizes scientific, medical, and business insights to guide high-impact decisions.
• Execution Excellence: Ensures disciplined planning, operational rigor, and delivery of commitments.
• Communication Mastery: Adjusts tone, style, and depth for executive, scientific, regulatory, and patient-facing audiences.
• High-Performance Team Leadership: Develops, motivates, and elevates team members; fosters accountability and growth.
• High Personal Accountability: Assumes accountability for actions; results-oriented; leads by example; champions assigned areas while remaining detail-oriented.
• Leads with urgency: Proactively anticipates and responds to challenges and opportunities; reduces cycle times and white space; action-oriented.

How We’ll Take Care Of You

• Generous annual leave and reward plans.
• Flexible working schedules (dependent on role).
• Access to tailored health support and meaningful ways to give back to the community.
• Twist, a career development platform offering learning programs, short-term projects, and internal growth opportunities.
• Culture that empowers exploration, evolution, and prioritization of wellbeing.