Vice President, Asset Team Leader

About the Company

Arvinas is a biotechnology company dedicated to improving the lives of patients suffering from debilitating and life-threatening diseases through the discovery, development, and commercialization of therapies that degrade disease-causing proteins. Arvinas uses its proprietary PROTAC Discovery Engine platform to engineer PROteolysis TArgeting Chimeras (PROTACs), designed to harness the body’s natural protein disposal system to selectively and efficiently degrade and remove disease-causing proteins.

This approach has enabled Arvinas to build a broad pipeline of investigational therapies across oncology and neurodegenerative diseases, including:

• ARV-102, targeting LRRK2 for neurodegenerative diseases;
• ARV-806, targeting KRAS G12D for mutated cancers, including pancreatic, colorectal, and non-small cell lung cancers;
• ARV-393, targeting BCL6 for relapsed/refractory non-Hodgkin Lymphoma;
• ARV-027, targeting the polyglutamine-expanded androgen receptor (polyQ-AR) in skeletal muscle for spinal bulbar muscular atrophy;
• Vepdegestrant, targeting the estrogen receptor for patients with locally advanced or metastatic ER+/HER2- breast cancer.

In May 2026, Arvinas achieved a major milestone with the first-ever U.S. Food and Drug Administration (FDA) approval of a PROTAC protein degrader therapy, marking a significant advancement for the field and demonstrating the therapeutic potential of targeted protein degradation. #TeamArvinas values diverse thoughts and perspectives, fostering an environment of innovation, creativity, and mission-driven work.

Arvinas is headquartered in New Haven, Connecticut.

About the Role

Arvinas is seeking a highly experienced Development Asset Team Leader to apply expert-level knowledge of biology and the biological mechanisms of drug development. This role leads cross-functional development teams accountable for the scientific strategy and seamless execution of early oncology development programs across all phases of drug development.

The successful candidate will apply deep expertise in biological sciences to recommend and drive the strategy of oncology assets and execution against planned timelines for early, mid-stage, and late-stage assets. This role reports to the SVP, Asset Strategy and Team Leadership and can be remote, hybrid, or located at our headquarters in New Haven, CT.

Responsibilities

• Apply relevant and up-to-date knowledge of biology, biological mechanisms of disease, and drug development to lead drug development strategy creation, achieve development milestones, and maximize the long-term value of assets.
• Lead the development of long-range objectives and specify strategies and actions to achieve them as part of the Integrated Development Plan with a multidisciplinary matrixed team.
• Lead alignment on plans with governance and executive management; communicate with senior leaders, peers, and functional representatives.
• Collaborate with functional leads to create and evaluate detailed scenario plans based on the external landscape and business needs; negotiate with and influence key internal and external stakeholders.
• Process and interpret biological and scientific information and data to continually reassess the drug development strategy and operational plan.
• Lead the External Engagement subteam to ensure assets are represented externally in alignment with Arvinas corporate and asset strategies, including publication and congress planning, KOL and advocacy engagement, and collaborations and partnerships.
• Represent the employer in a technical capacity at conferences.
• Use scientific background and advanced understanding of biological systems to lead the team in decision-making, problem-solving, and coordinating strategic and operational activities across Clinical Research, Clinical Operations, Regulatory, CMC, New Product Planning, and Project Management.
• Analyze biological, preclinical, and clinical information and data to identify trends or relationships among variables to choose optimal solutions and solve problems.
• Collaborate with the Project Manager on program progress, cost, resource allocation, timelines, and risk management; proactively identify risks, resolve issues, and optimize performance.
• Estimate and determine the time, costs, and resources needed for work activities; monitor and control resources.
• Evaluate scientific and biological information to determine compliance with standards; review reports and proposals for accuracy, adequacy, or adherence to policies, regulations, or scientific standards.
• Lead cross-functional oncology asset teams and act as the main point of contact and program representative to executive management.
• Interpret biological and scientific information and data for senior leaders and others in the organization to explain its meaning and application.
• Work closely with Business Development and Alliance Management on partnership opportunities and partnered programs.
• Represent programs at governance and decision-making meetings.
• Lead and/or support corporate objectives, including Board meeting preparation, earnings preparations, and corporate presentations.
• Drive team objective setting, prioritization, and performance to ensure adherence to plan and strategy.
• Coach and develop others; provide consultation and advice using knowledge of drug development and scientific experience.
• Create a positive team environment to achieve high performance by instilling trust, ensuring clear and transparent communications, and building consensus behind the overall goal/vision for the programs.
• Organize, plan, and prioritize the work of the team to align with specific goals and endorsed plans.
• Partner with Research to provide scientific and drug development experience as programs advance out of exploratory research and into development.

Requirements

• Advanced education in biology or a closely related scientific field of study.
• Significant oncology drug development and scientific leadership experience in the biotechnology/pharmaceutical industry.
• Minimum of 15 years of relevant experience in the biotechnology/pharmaceutical industry, with at least 5 years in a scientific leadership role leading cross-functional drug development asset teams.
• Leadership experience across all phases of drug development in the oncology therapeutic area, grounded in a strong foundation in biology.
• Experience in more than one drug development discipline.
• Experience in hematology oncology preferred.
• Proven ability to apply biological expertise and scientific rigor to lead and influence data interpretation, data-driven strategy planning, and implementation.
• A proactive and strategic thinker with strong decision-making skills.
• Proven ability to function effectively across a matrix organization with multiple stakeholders and constituents, focusing the team toward its goals.
• Demonstrated experience in successfully leading teams: running them effectively, efficiently, and on target.
• Ability to work cooperatively within a cross-functional, partially virtual team setting; strong interpersonal communication skills.
• Strong leadership and communication skills (including presentation skills) with success in influencing all levels cross-functionally.
• Excellent business acumen and judgment with demonstrated ability to align teams to corporate strategy to achieve business and project objectives.
• Highly collaborative with outstanding relationship-building skills.

Qualifications

Bachelor’s degree in biology or a closely related life science field (e.g., Microbiology, Chemistry, Clinical Research, or Health Science) required, with a minimum of 15 years of relevant experience in the biotechnology/pharmaceutical industry, including at least 5 years in a scientific leadership role. Specific training in an area of drug development, such as Clinical Research, is required. Equivalent combination of education and experience may be considered.

The duties of this role are generally conducted in a combination of company office and home office environments. Employees must be able, with or without accommodation, to:

• Lift/carry 15/30 pounds unassisted/assisted;
• Work comfortably in a controlled environment with and around biological, infectious, and hazardous materials;
• Gown/degown PPE;
• Use a computer;
• Engage in communications via phone, video, and electronic messaging;
• Engage in problem-solving, analysis, and dialogue;
• Collaborate with others;
• Maintain general availability during standard business hours.

Benefits

Arvinas offers a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness, and financial security of employees and their families. Benefits include:

• Group medical, vision, and dental coverage;
• Group and supplemental life insurance;
• Additional benefits (details available upon inquiry).